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Found 1857 with Last Name = 'schick' and Initial = 'h'
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50100983(CHEMBL3326224)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239934(US9403767, 117)
Affinity DataKi:  0.130nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101099(CHEMBL3326228)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101306(CHEMBL3326229)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177911(US9120797, 10 | US9120797, 9)
Affinity DataKi:  0.260nM ΔG°:  -54.7kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50100983(CHEMBL3326224)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101088(CHEMBL3326220)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177903(US9120797, 1 | US9120797, 2 | US9120797, 3)
Affinity DataKi:  0.300nM ΔG°:  -54.4kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50100983(CHEMBL3326224)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239934(US9403767, 117)
Affinity DataKi:  0.350nM ΔG°:  -54.0kJ/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM177911(US9120797, 10 | US9120797, 9)
Affinity DataKi:  0.360nM ΔG°:  -53.9kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101152(CHEMBL3326232)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101099(CHEMBL3326228)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101091(CHEMBL3326223)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101096(CHEMBL3325961)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239911(US9403767, 76 | US9403767, 77)
Affinity DataKi:  0.400nM ΔG°:  -53.6kJ/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50100991(CHEMBL3325879)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101088(CHEMBL3326220)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM177935(US9120797, 33)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177935(US9120797, 33)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239921(US9403767, 99)
Affinity DataKi:  0.540nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101306(CHEMBL3326229)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177903(US9120797, 1 | US9120797, 2 | US9120797, 3)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM177903(US9120797, 1 | US9120797, 2 | US9120797, 3)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50100983(CHEMBL3326224)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM177955(US9120797, 53)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239925(US9403767, 104 | US9403767, 105)
Affinity DataKi:  0.650nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101095(CHEMBL3325957)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50100993(CHEMBL3325881)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM177936(US9120797, 34)
Affinity DataKi:  0.700nM ΔG°:  -52.3kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239911(US9403767, 76 | US9403767, 77)
Affinity DataKi:  0.710nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239914(US9403767, 85)
Affinity DataKi:  0.810nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101095(CHEMBL3325957)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177948(US9120797, 46)
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101096(CHEMBL3325961)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101152(CHEMBL3326232)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101090(CHEMBL3326222)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177955(US9120797, 53)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101100(CHEMBL3325962)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177934(US9120797, 32)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM177947(US9120797, 45)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239867(US9403767, 20 | US9403767, 21)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177916(US9120797, 14 | US9120797, 15)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239925(US9403767, 104 | US9403767, 105)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239921(US9403767, 99)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM177925(US9120797, 23)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM177930(US9120797, 28)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239887(US9403767, 45)
Affinity DataKi:  1.24nM ΔG°:  -50.8kJ/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239865(US9403767, 18)
Affinity DataKi:  1.25nM ΔG°:  -50.8kJ/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM239892(US9403767, 50 | US9403767, 51)
Affinity DataKi:  1.28nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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