Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of human PR3 using keto-D-DY-FRET as substrateMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal His-tagged human FPPS (1 to 353 residues) expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 171nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 476nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of human PR3 using keto-D-DY-FRET as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 548nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 926nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of human PR3 using D-DY-FRET as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human PR3 using D-DY-FRET as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of human PR3 using D-DY-FRET as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataIC50: 2.86E+4nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair