Affinity DataKi: 0.00600nMAssay Description:Inhibition of EGFRChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of CaM-KKbetaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of human JNK1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human JNK2Checked by AuthorMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of human myosin light chain kinaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of GSK3-betaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of adhenosine kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Inhibition of Cdk1/cyclin B1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of GSK3-betaChecked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 52nMAssay Description:Inhibition of human JNK3Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of Cdk7/cyclin HChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of p160ROCKChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of AblChecked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 310nMAssay Description:Inhibition of p38alphaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Binding affinity to ERK1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Inhibition of ERK2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Inhibition of ERK1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Binding affinity to ERK2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 318nMAssay Description:Inhibition of PKCdeltaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 530nMAssay Description:Inhibition of ERK2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of PKCalphaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of FynChecked by AuthorMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of AKTChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of EphB3Checked by AuthorMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 3.80E+3nMAssay Description:Inhibition of myosin light chain kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 7.40E+3nMAssay Description:Inhibition of myosin light chain kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 1.01E+4nMAssay Description:Binding affinity at MLCKChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of CaM-KKbetaChecked by AuthorMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 2.83E+4nMAssay Description:Binding affinity at MLCKChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 2.97E+4nMAssay Description:Inhibition of CaM-KKbetaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.83E+4nMAssay Description:Inhibition of casein kinase 1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+4nMAssay Description:Inhibition of casein kinase 1Checked by AuthorMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKi: 1.50E+5nMAssay Description:Binding affinity at MLCKChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of wild type EGFRChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0250nMAssay Description:Inhibition of EGFRChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of wild type EGFRChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of GSK3-betaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of GSK3-betaChecked by AuthorMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of MKK1Checked by AuthorMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human VEGFR1 in HUVEC cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of JAK2Checked by AuthorMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Tyk2Checked by AuthorMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human VEGFR2 in HUVEC cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3KChecked by AuthorMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of p110-alpha PI kinaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of PKCbetaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of PKCalphaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of PKCgammaChecked by AuthorMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of VEGFR2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ErbB1Checked by AuthorMore data for this Ligand-Target Pair