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Found 96 with Last Name = 'sheldrake' and Initial = 'pw'
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401448(CHEMBL2203764)
Affinity DataIC50:  4nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401447(CHEMBL2203767)
Affinity DataIC50:  6nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401446(CHEMBL2207499)
Affinity DataIC50:  6nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401445(CHEMBL2203765)
Affinity DataIC50:  7nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401444(CHEMBL2203766)
Affinity DataIC50:  9nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106952(US8592581, 3)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401443(CHEMBL2203770)
Affinity DataIC50:  11nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401442(CHEMBL2203768)
Affinity DataIC50:  12nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401441(CHEMBL2207518)
Affinity DataIC50:  13nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401440(CHEMBL2207506)
Affinity DataIC50:  15nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106950(US8592581, 1)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106953(US8592581, 4)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401439(CHEMBL2207504)
Affinity DataIC50:  22nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401438(CHEMBL2203775)
Affinity DataIC50:  26nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401437(CHEMBL2207505)
Affinity DataIC50:  27nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401421(CHEMBL2207503)
Affinity DataIC50:  30nMAssay Description:Inhibition of Aurora A kinase autophosphorylation at T288 in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401436(CHEMBL2203769)
Affinity DataIC50:  34nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401435(CHEMBL2207516)
Affinity DataIC50:  35nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401421(CHEMBL2207503)
Affinity DataIC50:  38nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106958(US8592581, 9)
Affinity DataIC50:  40nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106960(US8592581, 11)
Affinity DataIC50:  40nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106956(US8592581, 7)
Affinity DataIC50:  40nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401434(CHEMBL2207500)
Affinity DataIC50:  40nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401433(CHEMBL2207515)
Affinity DataIC50:  41nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401432(CHEMBL2207514)
Affinity DataIC50:  45nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401431(CHEMBL2207517)
Affinity DataIC50:  45nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401430(CHEMBL2203774)
Affinity DataIC50:  47nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106959(US8592581, 10)
Affinity DataIC50:  50nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106961(US8592581, 12)
Affinity DataIC50:  50nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106955(US8592581, 6)
Affinity DataIC50:  50nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401429(CHEMBL2207501)
Affinity DataIC50:  52nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401428(CHEMBL2203773)
Affinity DataIC50:  54nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106952(US8592581, 3)
Affinity DataIC50:  60nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401427(CHEMBL2207508)
Affinity DataIC50:  68nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106953(US8592581, 4)
Affinity DataIC50:  80nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401426(CHEMBL2203771)
Affinity DataIC50:  87nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106965(US8592581, 16)
Affinity DataIC50:  90nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106950(US8592581, 1)
Affinity DataIC50:  90nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401425(CHEMBL2207502)
Affinity DataIC50:  93nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106950(US8592581, 1)
Affinity DataIC50:  100nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106952(US8592581, 3)
Affinity DataIC50:  100nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401424(CHEMBL2207512)
Affinity DataIC50:  118nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106953(US8592581, 4)
Affinity DataIC50:  120nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401423(CHEMBL2203772)
Affinity DataIC50:  130nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401422(CHEMBL2207513)
Affinity DataIC50:  147nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401421(CHEMBL2207503)
Affinity DataIC50:  148nMAssay Description:Inhibition of Aurora B kinase-mediated Histone H3 phosphorylation at S10 in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106957(US8592581, 8)
Affinity DataIC50:  160nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106960(US8592581, 11)
Affinity DataIC50:  250nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106955(US8592581, 6)
Affinity DataIC50:  270nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel

US Patent
LigandPNGBDBM106963(US8592581, 14)
Affinity DataIC50:  290nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In DepthDetails US Patent
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