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Found 875 with Last Name = 'song' and Initial = 'ks'
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313283(1-{2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-py...)
Affinity DataKi:  0.810nMAssay Description:Inhibition of 5-HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313283(1-{2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-py...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313284((S)-2-((7-fluoro-2,3-dihydro-1H-inden-4-yloxy)meth...)
Affinity DataKi:  21nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313284((S)-2-((7-fluoro-2,3-dihydro-1H-inden-4-yloxy)meth...)
Affinity DataKi:  86nMAssay Description:Inhibition of 5-HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50135168(3,4,5-Trihydroxy-benzoic acid (2R,3S)-5,7-dihydrox...)
Affinity DataKi:  170nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50135163(3,4,5-Trihydroxy-benzoic acid (2S,3S)-5,7-dihydrox...)
Affinity DataKi:  210nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 1(Homo sapiens (Human))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50269564(5,6,5',6'-tetrahydroxy[3,3']bibenzofuranyl-2,2'-di...)
Affinity DataKi:  290nMAssay Description:Inhibition of Flavobacterium meningosepticum PEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50018962(CHEMBL3287409)
Affinity DataKi:  4.28E+3nMAssay Description:Non-competitive inhibition of BACE1 (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50018959(Boeravinone D)
Affinity DataKi:  5.01E+3nMAssay Description:Non-competitive inhibition of BACE1 (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50241052(1,2,3,4,6-Pgg | 1,2,3,4,6-pentakis-O-(3,4,5-trihyd...)
Affinity DataKi:  5.13E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50135164(3,4,5-Trihydroxy-benzoic acid (2S,3S)-2-(3,4-dihyd...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibitory activity of the compound against recombinant human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50250989(CHEMBL450745 | eugeniin)
Affinity DataKi:  6.84E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159472(US9034921, E114)
Affinity DataIC50:  0.308nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159516(US9034921, E158 | US9340521, E024)
Affinity DataIC50:  0.366nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159528(US9034921, E171 | US9340521, E028)
Affinity DataIC50:  0.366nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159528(US9034921, E171 | US9340521, E028)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells by methyl-alpha-D-glucopyranoside assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159520(US9034921, E162 | US9340521, E026)
Affinity DataIC50:  0.404nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159387(US9034921, E001 | US9340521, E001)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells by methyl-alpha-D-glucopyranoside assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159458(US9034921, E098)
Affinity DataIC50:  0.454nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159529(US9034921, E172)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells by methyl-alpha-D-glucopyranoside assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159529(US9034921, E172)
Affinity DataIC50:  0.463nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159474(US9034921, E116)
Affinity DataIC50:  0.475nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM20880((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM20880((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM20880((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells by methyl-alpha-D-glucopyranoside assayMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM20880((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM20880((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159468(US9034921, E110)
Affinity DataIC50:  0.504nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159394(US9034921, E008 | US9340521, E006)
Affinity DataIC50:  0.551nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159471(US9034921, E113)
Affinity DataIC50:  0.551nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159599(US9034921, E242 | US9340521, E036)
Affinity DataIC50:  0.552nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50275414(2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...)
Affinity DataIC50:  0.570nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159537(US9034921, E180)
Affinity DataIC50:  0.574nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of CYP2D6 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159464(US9034921, E106)
Affinity DataIC50:  0.616nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159595(US9034921, E238 | US9340521, E033)
Affinity DataIC50:  0.627nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159455(US9034921, E095)
Affinity DataIC50:  0.628nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159451(US9034921, E091)
Affinity DataIC50:  0.629nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159521(US9034921, E163 | US9340521, E027)
Affinity DataIC50:  0.651nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159390(US9034921, E004 | US9340521, E003)
Affinity DataIC50:  0.661nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159476(US9034921, E118)
Affinity DataIC50:  0.678nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159391(US9034921, E005 | US9340521, E004)
Affinity DataIC50:  0.680nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells by methyl-alpha-D-glucopyranoside assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159391(US9034921, E005 | US9340521, E004)
Affinity DataIC50:  0.681nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50325211(2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...)
Affinity DataIC50:  0.681nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159503(US9034921, E145 | US9340521, E020)
Affinity DataIC50:  0.685nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159490(US9034921, E132)
Affinity DataIC50:  0.706nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159403(US9034921, E020)
Affinity DataIC50:  0.715nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159596(US9034921, E239)
Affinity DataIC50:  0.718nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159403(US9034921, E020)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells by methyl-alpha-D-glucopyranoside assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM50333628((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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