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Found 80 with Last Name = 'stoll' and Initial = 'f'
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118338(US8653111, 62)
Affinity DataIC50:  50nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM105221(US8580778, 21)
Affinity DataIC50:  70nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM105220(US8580778, 20)
Affinity DataIC50:  90nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM105219(US8580778, 17)
Affinity DataIC50:  130nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM105224(US8580778, 29)
Affinity DataIC50:  170nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM105222(US8580778, 25)
Affinity DataIC50:  180nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3527(US8524699, 18)
Affinity DataIC50:  180nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118341(US8653111, 85)
Affinity DataIC50:  190nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109268(US8609698, 10)
Affinity DataIC50:  260nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118328(US8653111, 7)
Affinity DataIC50:  340nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118344(US8653111, 103)
Affinity DataIC50:  350nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118346(US8653111, 129)
Affinity DataIC50:  360nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM105223(US8580778, 26)
Affinity DataIC50:  380nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3543(US8524699, 16)
Affinity DataIC50:  480nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118339(US8653111, 72)
Affinity DataIC50:  490nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118329(US8653111, 10)
Affinity DataIC50:  500nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM105217(US8580778, 5)
Affinity DataIC50:  540nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118331(US8653111, 17)
Affinity DataIC50:  560nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118347(US8653111, 166)
Affinity DataIC50:  690nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3555(US8524699, 3)
Affinity DataIC50:  700nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118345(US8653111, 113)
Affinity DataIC50:  740nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118330(US8653111, 12)
Affinity DataIC50:  750nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM105218(US8580778, 9)
Affinity DataIC50:  760nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118333(US8653111, 45)
Affinity DataIC50:  780nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM105216(US8580778, 2)
Affinity DataIC50:  880nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3591(US8524699, 7)
Affinity DataIC50:  880nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3623(US8524699, 28)
Affinity DataIC50:  890nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109271(US8609698, 65)
Affinity DataIC50:  900nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109269(US8609698, 18)
Affinity DataIC50:  910nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3629(US8524699, 46)
Affinity DataIC50:  930nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118337(US8653111, 61)
Affinity DataIC50:  1.10E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3643(US8524699, 44)
Affinity DataIC50:  1.12E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118334(US8653111, 50)
Affinity DataIC50:  1.40E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118336(US8653111, 60)
Affinity DataIC50:  1.40E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109272(US8609698, 80)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3644(US8524699, 55)
Affinity DataIC50:  1.70E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118343(US8653111, 101)
Affinity DataIC50:  1.70E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118332(US8653111, 43)
Affinity DataIC50:  1.80E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118340(US8653111, 83)
Affinity DataIC50:  1.90E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118335(US8653111, 55)
Affinity DataIC50:  2.00E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3698(US8524699, 22)
Affinity DataIC50:  2.70E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3723(US8524699, 6)
Affinity DataIC50:  2.80E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118342(US8653111, 91)
Affinity DataIC50:  2.80E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109270(US8609698, 22)
Affinity DataIC50:  3.24E+3nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109273(US8609698, 89)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3734(US8524699, 26)
Affinity DataIC50:  4.00E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109267(US8609698, 8)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109266(US8609698, 5)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM281728((+)-3-(4-Chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4...)
Affinity DataEC50:  22nMAssay Description:Soluble guanylate cyclase (sGC) converts on stimulation GTP into cGMP and pyrophosphate (PPi). PPi is detected with the aid of the assay described be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM281728((+)-3-(4-Chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4...)
Affinity DataEC50:  89nMAssay Description:Soluble guanylate cyclase (sGC) converts on stimulation GTP into cGMP and pyrophosphate (PPi). PPi is detected with the aid of the assay described be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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