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Found 167 with Last Name = 'taylor' and Initial = 'rd'
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139913(US8895745, 375)
Affinity DataIC50:  0.490nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139918(US8895745, 401)
Affinity DataIC50:  0.704nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139909(US8895745, 310)
Affinity DataIC50:  0.780nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139914(US8895745, 378)
Affinity DataIC50:  0.790nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480105(CHEMBL496201)
Affinity DataIC50:  1nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480108(CHEMBL496009)
Affinity DataIC50:  1nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139920(US8895745, 412)
Affinity DataIC50:  1.24nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139924(US8895745, 402)
Affinity DataIC50:  1.60nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139915(US8895745, 384)
Affinity DataIC50:  1.90nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139921(US8895745, 416)
Affinity DataIC50:  2.18nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139922(US8895745, 421)
Affinity DataIC50:  2.60nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139923(US8895745, 422)
Affinity DataIC50:  3.30nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139908(US8895745, 59)
Affinity DataIC50:  3.30nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139917(US8895745, 399)
Affinity DataIC50:  4.74nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480091(CHEMBL523753)
Affinity DataIC50:  6nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480123(CHEMBL496612)
Affinity DataIC50:  7nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Ucb

Curated by ChEMBL
LigandPNGBDBM50591317(CHEMBL5191783)
Affinity DataIC50:  7nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Ucb

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50:  7nMAssay Description:Inhibition of PMX in Plasmodium falciparum 3D7 HA epitopeMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Ucb

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50:  7nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480092(CHEMBL522072)
Affinity DataIC50:  7nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480112(CHEMBL496020)
Affinity DataIC50:  8nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Ucb

Curated by ChEMBL
LigandPNGBDBM50591318(CHEMBL5204196)
Affinity DataIC50:  9nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480093(CHEMBL487717)
Affinity DataIC50:  10nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480124(CHEMBL496202)
Affinity DataIC50:  12nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480094(CHEMBL496414)
Affinity DataIC50:  12nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
The Institute Of Cancer Research

LigandPNGBDBM29709(Pyridoimidazolone, 5i)
Affinity DataIC50:  12nMpH: 7.2 T: 2°CAssay Description:The biological activities (IC50s) of the compounds were determined against the B-RAF (V600E) mutant enzyme in vitro. GST-MEK1, B-RAF (V600E), and inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480095(CHEMBL501686)
Affinity DataIC50:  14nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
The Institute Of Cancer Research

LigandPNGBDBM29705(Pyridoimidazolone, 5e)
Affinity DataIC50:  14nMpH: 7.2 T: 2°CAssay Description:The biological activities (IC50s) of the compounds were determined against the B-RAF (V600E) mutant enzyme in vitro. GST-MEK1, B-RAF (V600E), and inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Ucb

Curated by ChEMBL
LigandPNGBDBM50591315(CHEMBL5172999)
Affinity DataIC50:  15nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139910(US8895745, 329)
Affinity DataIC50:  15.8nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480127(CHEMBL496203)
Affinity DataIC50:  16nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139912(US8895745, 359)
Affinity DataIC50:  16.4nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480096(CHEMBL524068)
Affinity DataIC50:  17nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139916(US8895745, 396)
Affinity DataIC50:  18.3nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
The Institute Of Cancer Research

LigandPNGBDBM29708(Pyridoimidazolone, 5h)
Affinity DataIC50:  21nMpH: 7.2 T: 2°CAssay Description:The biological activities (IC50s) of the compounds were determined against the B-RAF (V600E) mutant enzyme in vitro. GST-MEK1, B-RAF (V600E), and inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480097(CHEMBL498025)
Affinity DataIC50:  21nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480098(CHEMBL496185)
Affinity DataIC50:  22nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
The Institute Of Cancer Research

LigandPNGBDBM29715(Pyridoimidazolone, 5o)
Affinity DataIC50:  22nMpH: 7.2 T: 2°CAssay Description:The biological activities (IC50s) of the compounds were determined against the B-RAF (V600E) mutant enzyme in vitro. GST-MEK1, B-RAF (V600E), and inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139911(US8895745, 354)
Affinity DataIC50:  22.2nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480116(CHEMBL522724)
Affinity DataIC50:  23nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480099(CHEMBL498459)
Affinity DataIC50:  23nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
The Institute Of Cancer Research

LigandPNGBDBM29701(Pyridoimidazolone, 5a)
Affinity DataIC50:  23nMpH: 7.2 T: 2°CAssay Description:The biological activities (IC50s) of the compounds were determined against the B-RAF (V600E) mutant enzyme in vitro. GST-MEK1, B-RAF (V600E), and inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM29701(Pyridoimidazolone, 5a)
Affinity DataIC50:  23nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480100(CHEMBL487718)
Affinity DataIC50:  24nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480115(CHEMBL496019)
Affinity DataIC50:  25nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
The Institute Of Cancer Research

LigandPNGBDBM29710(Pyridoimidazolone, 5j)
Affinity DataIC50:  27nMpH: 7.2 T: 2°CAssay Description:The biological activities (IC50s) of the compounds were determined against the B-RAF (V600E) mutant enzyme in vitro. GST-MEK1, B-RAF (V600E), and inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
The Institute Of Cancer Research

LigandPNGBDBM29723(Pyridoimidazolone, 5w)
Affinity DataIC50:  28nMpH: 7.2 T: 2°CAssay Description:The biological activities (IC50s) of the compounds were determined against the B-RAF (V600E) mutant enzyme in vitro. GST-MEK1, B-RAF (V600E), and inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
The Institute Of Cancer Research

LigandPNGBDBM29722(Pyridoimidazolone, 5v)
Affinity DataIC50:  29nMpH: 7.2 T: 2°CAssay Description:The biological activities (IC50s) of the compounds were determined against the B-RAF (V600E) mutant enzyme in vitro. GST-MEK1, B-RAF (V600E), and inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50480101(CHEMBL521725)
Affinity DataIC50:  30nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM139919(US8895745, 407)
Affinity DataIC50:  31nMpH: 7.5Assay Description:Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...More data for this Ligand-Target Pair
In DepthDetails US Patent
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