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Found 63 with Last Name = 'tedenborg' and Initial = 'l'
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50130261(6-(2-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-ethy...)
Affinity DataKi:  1.99nMAssay Description:Binding affinity for rat serotonin 5-HT7 receptor expressed in Sf9 cells using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224221(5-cyclopentyl-2-(2-fluorophenylamino)thiazol-4(5H)...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224216(2-(2-chlorophenylamino)-5-cyclopentylthiazol-4(5H)...)
Affinity DataKi:  6.30nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150686(CHEMBL182792 | [(R)-8-(2,6-Dimethoxy-phenyl)-chrom...)
Affinity DataKi:  6.44nMAssay Description:Binding affinity for rat serotonin 5-HT7 receptor expressed in Sf9 cells using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224207(2-(2-fluorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataKi:  7nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224202(5-cyclohexyl-2-(2-fluorophenylamino)thiazol-4(5H)-...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224208(2-(2-chlorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224203(2-(2-chlorophenylamino)-5-cyclohexylthiazol-4(5H)-...)
Affinity DataKi:  11nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224217(2-(2,5-difluorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataKi:  12nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224205(2-(2,6-dichlorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataKi:  13nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50160366((S)-6-(2,6-dimethylphenyl)-N,N-dimethylchroman-3-a...)
Affinity DataKi:  13.4nMAssay Description:Binding affinity for rat serotonin 5-HT7 receptor expressed in Sf9 cells using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224207(2-(2-fluorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataKi:  17nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224222(2-(2,4-dichlorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataKi:  18nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224212(5-isopropyl-2-(2-(trifluoromethyl)phenylamino)thia...)
Affinity DataKi:  23nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224200(2-(2,4-difluorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataKi:  26nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224213(2-(o-toluidino)-5-isopropylthiazol-4(5H)-one | CHE...)
Affinity DataKi:  27nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224211(5-isopropyl-2-(isoquinolin-5-ylamino)thiazol-4(5H)...)
Affinity DataKi:  32nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50160364(CHEMBL183676 | [(S)-6-(1-Methoxy-naphthalen-2-yl)-...)
Affinity DataKi:  75.9nMAssay Description:Binding affinity for rat serotonin 5-HT7 receptor expressed in Sf9 cells using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224206(5-isopropyl-2-(phenylamino)thiazol-4(5H)-one | CHE...)
Affinity DataKi:  110nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224207(2-(2-fluorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataKi:  140nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224215(2-(1H-indol-4-ylamino)-5-isopropylthiazol-4(5H)-on...)
Affinity DataKi:  210nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224223(5-isopropyl-2-(4-phenoxyphenylamino)thiazol-4(5H)-...)
Affinity DataKi:  220nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224201(2-(4-fluorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataKi:  340nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224220(2-(2-chlorophenylamino)-5-methylthiazol-4(5H)-one ...)
Affinity DataKi:  350nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50160365(CHEMBL427326 | [(S)-6-(2,6-Dimethoxy-phenyl)-chrom...)
Affinity DataKi:  367nMAssay Description:Binding affinity for rat serotonin 5-HT7 receptor expressed in Sf9 cells using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224225(5-isopropyl-2-(2-methylbenzo[d]thiazol-5-ylamino)t...)
Affinity DataKi:  510nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224210(2-(4-cyclohexylphenylamino)-5-isopropylthiazol-4(5...)
Affinity DataKi:  660nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50160362(CHEMBL180644 | Dimethyl-((S)-6-phenyl-chroman-3-yl...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for rat serotonin 5-HT7 receptor expressed in Sf9 cells using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224214(2-(1H-indazol-5-ylamino)-5-isopropylthiazol-4(5H)-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50160363(2-((S)-3-Dimethylamino-chroman-6-yl)-benzene-1,3-d...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for rat serotonin 5-HT7 receptor expressed in Sf9 cells using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224209(5-isopropyl-2-(2-methoxyphenylamino)thiazol-4(5H)-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224224(5-isopropyl-2-(pyridin-4-ylamino)thiazol-4(5H)-one...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224204(5-isopropyl-2-(pyridin-2-ylamino)thiazol-4(5H)-one...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224213(2-(o-toluidino)-5-isopropylthiazol-4(5H)-one | CHE...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human 11betaHSD1 in presence of 3% HSA by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224212(5-isopropyl-2-(2-(trifluoromethyl)phenylamino)thia...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human 11betaHSD1 in presence of 3% HSA by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224207(2-(2-fluorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataIC50: >10nMAssay Description:Inhibition of human 11betaHSD1 in presence of 3% HSA by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224208(2-(2-chlorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224207(2-(2-fluorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224216(2-(2-chlorophenylamino)-5-cyclopentylthiazol-4(5H)...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224221(5-cyclopentyl-2-(2-fluorophenylamino)thiazol-4(5H)...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224205(2-(2,6-dichlorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224217(2-(2,5-difluorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224212(5-isopropyl-2-(2-(trifluoromethyl)phenylamino)thia...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224203(2-(2-chlorophenylamino)-5-cyclohexylthiazol-4(5H)-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224222(2-(2,4-dichlorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224202(5-cyclohexyl-2-(2-fluorophenylamino)thiazol-4(5H)-...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224200(2-(2,4-difluorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224207(2-(2-fluorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224207(2-(2-fluorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataIC50:  97nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224213(2-(o-toluidino)-5-isopropylthiazol-4(5H)-one | CHE...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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