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Found 124 with Last Name = 'teufel' and Initial = 'dp'
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256265(CHEMBL4089486)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256283(CHEMBL4079711)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256264(CHEMBL4099333)
Affinity DataKi:  0.140nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256277(CHEMBL4093698)
Affinity DataKi:  0.150nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256286(CHEMBL4076199)
Affinity DataKi:  0.210nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256262(CHEMBL4070056)
Affinity DataKi:  0.25nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256260(CHEMBL4094403)
Affinity DataKi:  0.360nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256276(CHEMBL4079260)
Affinity DataKi:  0.390nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256284(CHEMBL4075544)
Affinity DataKi:  0.400nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256288(CHEMBL4085408)
Affinity DataKi:  0.440nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538252(CHEMBL4642167)
Affinity DataKi:  0.540nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256283(CHEMBL4079711)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256263(CHEMBL4088185)
Affinity DataKi:  1.30nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538266(CHEMBL4649686)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256277(CHEMBL4093698)
Affinity DataKi:  2nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538258(CHEMBL4641389)
Affinity DataKi:  2nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256287(CHEMBL4105318)
Affinity DataKi:  2.10nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256284(CHEMBL4075544)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538238(CHEMBL4642849)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538270(CHEMBL4634220)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256261(CHEMBL4059991)
Affinity DataKi:  3nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538273(CHEMBL4634551)
Affinity DataKi:  3.10nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256261(CHEMBL4059991)
Affinity DataKi:  3.40nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein(Sus scrofa)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256277(CHEMBL4093698)
Affinity DataKi:  3.60nMAssay Description:Inhibition of pig plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538264(CHEMBL4636597)
Affinity DataKi:  4.80nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538274(CHEMBL4637644)
Affinity DataKi:  5.10nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538260(CHEMBL4643355)
Affinity DataKi:  5.20nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538267(CHEMBL4634880)
Affinity DataKi:  5.5nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256262(CHEMBL4070056)
Affinity DataKi:  5.5nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538272(CHEMBL4636032)
Affinity DataKi:  5.70nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538239(CHEMBL4640044)
Affinity DataKi:  5.80nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538271(CHEMBL4648601)
Affinity DataKi:  5.80nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538263(CHEMBL4643893)
Affinity DataKi:  6.80nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538259(CHEMBL4637500)
Affinity DataKi:  9nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256276(CHEMBL4079260)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538265(CHEMBL4643498)
Affinity DataKi:  13nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538269(CHEMBL4635897)
Affinity DataKi:  15nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetKallikrein(Sus scrofa)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256276(CHEMBL4079260)
Affinity DataKi:  22nMAssay Description:Inhibition of pig plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538254(CHEMBL4638336)
Affinity DataKi:  27nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256260(CHEMBL4094403)
Affinity DataKi:  30nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538268(CHEMBL4642586)
Affinity DataKi:  35nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538247(CHEMBL4642437)
Affinity DataKi:  39nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Mus musculus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256262(CHEMBL4070056)
Affinity DataKi:  45nMAssay Description:Inhibition of recombinant mouse C-terminal 6His-tagged plasma kallikrein (20 to 638 residues) using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Mus musculus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256261(CHEMBL4059991)
Affinity DataKi:  54nMAssay Description:Inhibition of recombinant mouse C-terminal 6His-tagged plasma kallikrein (20 to 638 residues) using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538256(CHEMBL4644287)
Affinity DataKi:  56nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538241(CHEMBL4639187)
Affinity DataKi:  82nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538255(CHEMBL4637860)
Affinity DataKi:  83nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538251(CHEMBL4645672)
Affinity DataKi:  83nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538257(CHEMBL4647046)
Affinity DataKi:  101nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538240(CHEMBL4641388)
Affinity DataKi:  115nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
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