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Found 766 with Last Name = 'thirup' and Initial = 's'
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251493((2S,4S)-1-(2-(1-(4-cyano-3,5-difluorophenyl)piperi...)
Affinity DataKi:  1nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198694(US9221796, 23b)
Affinity DataKi:  1.40nM ΔG°:  -54.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198665(US9221796, 2b)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198665(US9221796, 2b)
Affinity DataKi:  1.40nM ΔG°:  -54.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198694(US9221796, 23b)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198687(US9221796, 18b)
Affinity DataKi:  1.5nM ΔG°:  -54.6kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198685(US9221796, 17)
Affinity DataKi:  1.60nM ΔG°:  -54.4kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198681(US9221796, 13b)
Affinity DataKi:  1.60nM ΔG°:  -54.4kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198835(US9221796, 116)
Affinity DataKi:  2nM ΔG°:  -53.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198724(US9221796, 45, P-4)
Affinity DataKi:  2.5nM ΔG°:  -53.2kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198834(US9221796, 115)
Affinity DataKi:  2.70nM ΔG°:  -53.0kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423269(US10501451, Example 2, P-1 | US10501451, Example 2...)
Affinity DataKi:  2.79nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423269(US10501451, Example 2, P-1 | US10501451, Example 2...)
Affinity DataKi:  2.79nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423291(US10501451, Example 14, P-1 | US10501451, Example ...)
Affinity DataKi:  2.80nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423291(US10501451, Example 14, P-1 | US10501451, Example ...)
Affinity DataKi:  2.80nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198692(US9221796, 22)
Affinity DataKi:  2.90nM ΔG°:  -52.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198837(US9221796, 117, P-2)
Affinity DataKi:  2.90nM ΔG°:  -52.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198663(US9221796, 1)
Affinity DataKi:  3nM ΔG°:  -52.7kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423285(US10501451, Example 11, P-1 | US10501451, Example ...)
Affinity DataKi:  3.06nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423285(US10501451, Example 11, P-1 | US10501451, Example ...)
Affinity DataKi:  3.06nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198722(US9221796, 45, P-2)
Affinity DataKi:  3.10nM ΔG°:  -52.6kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423283(US10501451, Example 10, P-1 | US10501451, Example ...)
Affinity DataKi:  3.20nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423283(US10501451, Example 10, P-1 | US10501451, Example ...)
Affinity DataKi:  3.20nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198732(US9221796, 47, P-4)
Affinity DataKi:  3.40nM ΔG°:  -52.4kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198832(US9221796, 114, P-1)
Affinity DataKi:  3.5nM ΔG°:  -52.3kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198772(BDBM198773 | US9221796, 64)
Affinity DataKi:  3.60nM ΔG°:  -52.2kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198731(US9221796, 47, P-3)
Affinity DataKi:  3.80nM ΔG°:  -52.1kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198789(US9221796, 81)
Affinity DataKi:  3.80nM ΔG°:  -52.1kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423287(US10501451, Example 12, P-1 | US10501451, Example ...)
Affinity DataKi:  3.90nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423287(US10501451, Example 12, P-1 | US10501451, Example ...)
Affinity DataKi:  3.90nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198688(US9221796, 19)
Affinity DataKi:  3.90nM ΔG°:  -52.0kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198728(US9221796, 46, P-4)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198679(US9221796, 12)
Affinity DataKi:  4nM ΔG°:  -52.0kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198728(US9221796, 46, P-4)
Affinity DataKi:  4nM ΔG°:  -52.0kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423289(US10501451, Example 13, P-1 | US10501451, Example ...)
Affinity DataKi:  4.03nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423289(US10501451, Example 13, P-1 | US10501451, Example ...)
Affinity DataKi:  4.03nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423267(US10501451, Example 1, P-1 | US10501451, Example 1...)
Affinity DataKi:  4.08nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423267(US10501451, Example 1, P-1 | US10501451, Example 1...)
Affinity DataKi:  4.08nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198726(US9221796, 46, P-2)
Affinity DataKi:  4.30nM ΔG°:  -51.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198726(US9221796, 46, P-2)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423273(US10501451, Example 5, P-1 | US10501451, Example 5...)
Affinity DataKi:  4.37nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423273(US10501451, Example 5, P-1 | US10501451, Example 5...)
Affinity DataKi:  4.37nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50330324(CHEMBL4170867)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198668(US9221796, 5)
Affinity DataKi:  4.40nM ΔG°:  -51.7kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198829(BDBM198830 | US9221796, 112, P-1)
Affinity DataKi:  4.40nM ΔG°:  -51.7kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198805(BDBM198821 | US9221796, 95, P-2)
Affinity DataKi:  4.60nM ΔG°:  -51.6kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198670(US9221796, 6b)
Affinity DataKi:  4.70nM ΔG°:  -51.5kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198695(US9221796, 24)
Affinity DataKi:  4.70nM ΔG°:  -51.5kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198703(US9221796, 30)
Affinity DataKi:  4.70nM ΔG°:  -51.5kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423277(US10501451, Example 7, P-1 | US10501451, Example 7...)
Affinity DataKi:  4.98nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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