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Found 358 with Last Name = 'toyoda' and Initial = 't'
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM126701(US8778970, 5-9)
Affinity DataKi:  0.270nM ΔG°:  -54.6kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM126698(US8778970, 5-6)
Affinity DataKi:  0.270nM ΔG°:  -54.6kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322074(1-{1-(cyclohexylmethyl)-5-[(2,5-difluorobenzyl)oxy...)
Affinity DataKi:  0.340nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322074(1-{1-(cyclohexylmethyl)-5-[(2,5-difluorobenzyl)oxy...)
Affinity DataKi:  0.340nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM50460160(CHEMBL4229131)
Affinity DataKi:  0.410nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322125(1-(5-[(2,5-difluorobenzyl)oxy]-1-{[1-(trifluoro-me...)
Affinity DataKi:  0.5nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322125(1-(5-[(2,5-difluorobenzyl)oxy]-1-{[1-(trifluoro-me...)
Affinity DataKi:  0.5nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322090(US10183913, Example 242 | US11312688, Example 242 ...)
Affinity DataKi:  0.520nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322090(US10183913, Example 242 | US11312688, Example 242 ...)
Affinity DataKi:  0.520nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM550841(US11312688, Example 400)
Affinity DataKi:  0.540nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322118(US10183913, Example 400)
Affinity DataKi:  0.540nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322097(1-{5-[(2,5-difluorobenzyl)oxy]-1-(3-methylbutyl)-1...)
Affinity DataKi:  0.590nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322097(1-{5-[(2,5-difluorobenzyl)oxy]-1-(3-methylbutyl)-1...)
Affinity DataKi:  0.590nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322122(1-(2-{5-[(5-Chloro-2-fluorobenzyl)oxy]-3-[(methyla...)
Affinity DataKi:  0.600nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM550845(1-(2-{5-[(5-Chloro-2-fluorobenzyl)oxy]-3-[(methyla...)
Affinity DataKi:  0.600nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322094(1-{5-[(2,5-difluorobenzyl)oxy]-1-(2,2-dimethylprop...)
Affinity DataKi:  0.660nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322094(1-{5-[(2,5-difluorobenzyl)oxy]-1-(2,2-dimethylprop...)
Affinity DataKi:  0.660nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM50460148(CHEMBL4226053)
Affinity DataKi:  0.670nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322096(1-{5-[(2,5-difluorobenzyl)oxy]-1-(3,3-dimethylbuty...)
Affinity DataKi:  0.690nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322096(1-{5-[(2,5-difluorobenzyl)oxy]-1-(3,3-dimethylbuty...)
Affinity DataKi:  0.690nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322083(1-{1-(cyclopentylmethyl)-5-[(2,5-difluorobenzyl)ox...)
Affinity DataKi:  0.710nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322079(US10183913, Example 124 | US11312688, Example 124 ...)
Affinity DataKi:  0.710nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322083(1-{1-(cyclopentylmethyl)-5-[(2,5-difluorobenzyl)ox...)
Affinity DataKi:  0.710nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322079(US10183913, Example 124 | US11312688, Example 124 ...)
Affinity DataKi:  0.710nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322132(1-{5-[(2,5-Difluorobenzyl)oxy]-1-(3-fluoro-3-methy...)
Affinity DataKi:  0.850nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322132(1-{5-[(2,5-Difluorobenzyl)oxy]-1-(3-fluoro-3-methy...)
Affinity DataKi:  0.850nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322103(1-[5-(Benzyloxy)-1-(1-cyclopentylethyl)-1H-pyrazol...)
Affinity DataKi:  0.860nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322103(1-[5-(Benzyloxy)-1-(1-cyclopentylethyl)-1H-pyrazol...)
Affinity DataKi:  0.860nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM126709(US8778970, 5-14)
Affinity DataKi:  0.880nM ΔG°:  -51.7kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322086(1-[5-(Benzyloxy)-1-(2-cyclopentylethyl)-1H-pyrazol...)
Affinity DataKi:  0.910nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322086(1-[5-(Benzyloxy)-1-(2-cyclopentylethyl)-1H-pyrazol...)
Affinity DataKi:  0.910nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322073(1-{1-(cyclohexylmethyl)-5-[(4-fluoro-2-methylbenzy...)
Affinity DataKi:  0.920nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322073(1-{1-(cyclohexylmethyl)-5-[(4-fluoro-2-methylbenzy...)
Affinity DataKi:  0.920nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322106(1-[5-(Benzyloxy)-1-(1-cyclohexyl-2-fluoroethyl)-1H...)
Affinity DataKi:  0.960nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322106(1-[5-(Benzyloxy)-1-(1-cyclohexyl-2-fluoroethyl)-1H...)
Affinity DataKi:  0.960nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322114(1-{1-(Cyclohexylmethyl)-5-[(2,5-difluorobenzyl)oxy...)
Affinity DataKi:  0.980nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM550837(1-{1-(Cyclohexylmethyl)-5-[(2,5-difluorobenzyl)oxy...)
Affinity DataKi:  0.980nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322119(US10183913, Example 405 | US11312688, Example 426)
Affinity DataKi:  0.990nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322120(US10183913, Example 426)
Affinity DataKi:  0.990nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM50460159(CHEMBL4226281)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322100(N-Methyl-1-{1-(3-methylbutyl)-5-[(2,4,5-trifluorob...)
Affinity DataKi:  1.10nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM126697(US8778970, 5-5)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322100(N-Methyl-1-{1-(3-methylbutyl)-5-[(2,4,5-trifluorob...)
Affinity DataKi:  1.10nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM50460149(CHEMBL4228477)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322107(US10183913, Example 331 | US11312688, Example 331 ...)
Affinity DataKi:  1.30nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM126700(US8778970, 5-8)
Affinity DataKi:  1.30nM ΔG°:  -50.7kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM126702(US8778970, 5-10)
Affinity DataKi:  1.30nM ΔG°:  -50.7kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322107(US10183913, Example 331 | US11312688, Example 331 ...)
Affinity DataKi:  1.30nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM50460147(CHEMBL4226031)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM322092(US10183913, Example 253 | US11312688, Example 253)
Affinity DataKi:  1.5nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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