TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 228nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 723nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells by densitometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 4.08E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 4.34E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 4.64E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells by densitometric analysisMore data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+4nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair