Compile Data Set for Download or QSAR
maximum 50k data
Found 66 with Last Name = 'uesugi' and Initial = 'm'
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082324((S)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082323(4-[4-(4-Fluoro-benzyl)-phenyl]-1-((E)-3-phenyl-all...)
Affinity DataIC50:  190nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50:  220nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)
Affinity DataIC50:  228nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)
Affinity DataIC50:  290nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataIC50:  300nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082320(4-(4-Phenoxy-phenyl)-1-((E)-3-phenyl-allyl)-piperi...)
Affinity DataIC50:  320nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082322(1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-...)
Affinity DataIC50:  360nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 1(Homo sapiens)
Teikyo University

Curated by ChEMBL
LigandPNGBDBM50351538(CHEMBL1824673)
Affinity DataIC50:  700nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351538(CHEMBL1824673)
Affinity DataIC50:  700nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 1(Homo sapiens)
Teikyo University

Curated by ChEMBL
LigandPNGBDBM50571643(CHEMBL4851466)
Affinity DataIC50:  723nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351539(CHEMBL1824674)
Affinity DataIC50:  900nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351538(CHEMBL1824673)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells by densitometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 1(Homo sapiens)
Teikyo University

Curated by ChEMBL
LigandPNGBDBM50571642(CHEMBL4876668)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 1(Homo sapiens)
Teikyo University

Curated by ChEMBL
LigandPNGBDBM50521013(CHEBI:17933 | Calcifediol)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 1(Homo sapiens)
Teikyo University

Curated by ChEMBL
LigandPNGBDBM50571644(CHEMBL4851396)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351541(CHEMBL1824676)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351540(CHEMBL1824675)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082320(4-(4-Phenoxy-phenyl)-1-((E)-3-phenyl-allyl)-piperi...)
Affinity DataIC50:  2.68E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351534(CHEMBL1824669)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50263669((1aS,7aS)-7-(hydroxyimino)-N-phenyl-1,1a,7,7a-tetr...)
Affinity DataIC50:  3.00E+3nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351535(CHEMBL1824670)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351529(CHEMBL1824664)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082323(4-[4-(4-Fluoro-benzyl)-phenyl]-1-((E)-3-phenyl-all...)
Affinity DataIC50:  3.38E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50:  4.08E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082324((S)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50:  4.34E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50:  4.64E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351536(CHEMBL1824671)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 1(Homo sapiens)
Teikyo University

Curated by ChEMBL
LigandPNGBDBM50351521(CHEMBL1824658)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM78179(2-(2-propyl-4-pyridyl)-4-(p-tolyl)thiazole;hydrobr...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351521(CHEMBL1824658)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351537(CHEMBL1824672)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351542(CHEMBL1824661)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351533(CHEMBL1824668)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351531(CHEMBL1824666)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351530(CHEMBL1824665)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351526(CHEMBL1616869)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289106(2-[(E)-Hydroxyimino]-1a,2-dihydro-1H-7-oxa-cyclopr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082322(1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM78179(2-(2-propyl-4-pyridyl)-4-(p-tolyl)thiazole;hydrobr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells by densitometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351528(CHEMBL1824663)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM93773(4-(4-chlorophenyl)-2-(2-propyl-4-pyridinyl)thiazol...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351524(CHEMBL1824660)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351527(CHEMBL1824662)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351532(CHEMBL1824667)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351518(CHEMBL1824655)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351519(CHEMBL1824656)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataIC50:  2.30E+4nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50351523(CHEMBL1824659)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 66 total ) | Next | Last >>
Jump to: