TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 9.13E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 730nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.49E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 580nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 750nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.05E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope
Curated by ChEMBL
Beckman Research Institute Of The City Of Hope
Curated by ChEMBL
Affinity DataKd: 3.80E+4nMAssay Description:Binding affinity to human 15N-labeled STEP PTP domain (281 to 563 residues) expressed in Escherichia coli OD2 by 1H,15N TROSY NMR spectral analysisMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 2.83E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.09E+4nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 6.10E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 2.39E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 680nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope
Curated by ChEMBL
Beckman Research Institute Of The City Of Hope
Curated by ChEMBL
Affinity DataKd: 8.00E+5nMAssay Description:Binding affinity to human STEP PTP domain (281 to 563 residues) expressed in Escherichia coli BL21(DE3) by ITCMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute
Curated by ChEMBL
The Beckman Research Institute
Curated by ChEMBL
Affinity DataEC50: 220nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair