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Found 27 with Last Name = 'valliant' and Initial = 'jf'
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50160305(CHEMBL3786632)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]23 from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50297675(CHEMBL551148 | N-(4-fluorobenzyl)-4-(4-(methylsulf...)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant human COX-2 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM220398(US9296708, 4, ARM-P4)
Affinity DataIC50:  9nMAssay Description:Displacement of [125I]23 from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50160294(CHEMBL3785709)
Affinity DataIC50:  14nMAssay Description:Displacement of [125I]23 from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50160293(CHEMBL3786463)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]23 from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50160295(CHEMBL3785786)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]23 from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM220400(US9296708, 6, ARM-P8)
Affinity DataIC50:  23nMAssay Description:Displacement of [125I]23 from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50160292(CHEMBL3785826)
Affinity DataIC50:  24nMAssay Description:Displacement of [125I]23 from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50160291(CHEMBL3786511)
Affinity DataIC50:  30nMAssay Description:Displacement of [125I]23 from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  40nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant human COX-2 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by fluoresc...More data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM17659((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...)
Affinity DataIC50:  52nMAssay Description:Displacement of [125I]23 from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50:  60nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50160296(CHEMBL3786678)
Affinity DataIC50:  98nMAssay Description:Displacement of [125I]23 from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50160303(CHEMBL3787537)
Affinity DataIC50:  123nMAssay Description:Displacement of [125I]23 from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50154401(CHEMBL3774612)
Affinity DataIC50:  850nMAssay Description:Inhibition of recombinant human COX-2 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50029616(5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50154400(CHEMBL3774538)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of recombinant human COX-2 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50154412(CHEMBL3775406)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50336971(5-(4-iodophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(t...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50154402(CHEMBL3775974)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50154399(CHEMBL3774963)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of recombinant human COX-2 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of ovine COX-1 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by fluorescence analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50154401(CHEMBL3774612)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-1 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by fluorescence analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50154400(CHEMBL3774538)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-1 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by fluorescence analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50154399(CHEMBL3774963)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-1 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by fluorescence analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50297675(CHEMBL551148 | N-(4-fluorobenzyl)-4-(4-(methylsulf...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-1 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by fluorescence analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed