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Found 101 with Last Name = 'van poecke' and Initial = 's'
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314845(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataKi:  12nMAssay Description:Competitive inhibition of human recombinant mitochondrial thymidine kinase 2 using ATP as substrate by Lineweaver-Burk plottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314848(3'-hexanoylamino-3'-deoxythymidine | CHEMBL1089836)
Affinity DataKi:  150nMAssay Description:Inhibition of thymidine kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50359625(CHEMBL1928435)
Affinity DataKi:  170nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314845(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataKi:  410nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burk plottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314839(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataKi:  2.10E+3nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50359621(CHEMBL1928431)
Affinity DataKi:  2.30E+3nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314837(3'-(4-Benzyl-1,2,3-triazol-1-yl)-3'-deoxy-beta-D-t...)
Affinity DataKi:  2.70E+3nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50359618(CHEMBL1928428)
Affinity DataKi:  2.80E+3nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314836(3'-(4-Phenyl-1,2,3-triazol-1-yl)-3'-deoxythymidine...)
Affinity DataKi:  4.20E+3nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50359627(CHEMBL1253612)
Affinity DataKi:  6.00E+3nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50359626(CHEMBL1928436)
Affinity DataKi:  9.00E+3nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314850(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-((2S,3S,5...)
Affinity DataKi:  9.90E+3nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50118628((R)-1-((R)-4-Azido-5-methylphosphate-tetrahydro-fu...)
Affinity DataKi:  1.00E+4nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK expressed in Escherichia coli NM554 by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50206491(1-beta-D-arabinofuranosyl-5-(2-bromovinyl)uracil |...)
Affinity DataKi:  1.04E+4nMAssay Description:Inhibition of thymidine kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50359622(CHEMBL1928432)
Affinity DataKi:  1.45E+4nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50359619(CHEMBL1928429)
Affinity DataKi:  1.50E+4nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50223817(5'-azido-5'-deoxy-alpha-D-thymidine | CHEMBL235305)
Affinity DataKi:  2.65E+4nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataKi:  2.80E+4nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50359628(CHEMBL1928437)
Affinity DataKi:  3.50E+4nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50359620(CHEMBL1928430)
Affinity DataKi:  4.50E+4nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50359623(CHEMBL1928433)
Affinity DataKi:  7.30E+4nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50359618(CHEMBL1928428)
Affinity DataKi:  9.50E+4nMAssay Description:Competitive inhibition of human TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate kinase(Mycobacterium tuberculosis)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50359624(CHEMBL1926703)
Affinity DataKi:  2.01E+5nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314845(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314840(3'-Deoxy-3'-(4-(3,4-dichlorophenyl)-1,2,3-triazol-...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314839(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181154(1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propy...)
Affinity DataIC50:  59nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181152(1-(4-chlorophenyl)-3-(N-hydroxyacetamido)propylpho...)
Affinity DataIC50:  99nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181148(1-(3,4-dichlorophenyl)-3-(N-hydroxyacetamido)propy...)
Affinity DataIC50:  119nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314838(3'-(4-Cyclopentylmethyl-1,2,3-triazol-1-yl)-3'-deo...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314850(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-((2S,3S,5...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181150(3-(N-hydroxyformamido)-1-(4-methoxyphenyl)propylph...)
Affinity DataIC50:  156nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314835(3'-(4-Butyl-1,2,3-triazol-1-yl)-3'-deoxy-beta-D-th...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314844(3'-Deoxy-3'-(4-phenyl-1,2,3-triazol-1-yl)-beta-(E)...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314837(3'-(4-Benzyl-1,2,3-triazol-1-yl)-3'-deoxy-beta-D-t...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181147(3-(N-hydroxyacetamido)-1-phenylpropylphosphonic ac...)
Affinity DataIC50:  311nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314836(3'-(4-Phenyl-1,2,3-triazol-1-yl)-3'-deoxythymidine...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181149(3-(N-hydroxyacetamido)-1-p-tolylpropylphosphonic a...)
Affinity DataIC50:  396nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314849(CHEMBL1091872 | N-methyl-4-((8-(5-methyl-2,4-dioxo...)
Affinity DataIC50:  400nMAssay Description:Inhibition of thymidine kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50181151(3-(N-hydroxyacetamido)-1-(4-methoxyphenyl)propylph...)
Affinity DataIC50:  459nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314845(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50:  460nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314840(3'-Deoxy-3'-(4-(3,4-dichlorophenyl)-1,2,3-triazol-...)
Affinity DataIC50:  990nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314842(3'-Deoxy-3'-(5-phenyl-1,2,3-triazol-1-yl)-beta-D-t...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314841(3'-(4-(2-Pyridine)-1,2,3-triazole-1-yl)-2'-deoxyth...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50118490(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of thymidine kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314839(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314836(3'-(4-Phenyl-1,2,3-triazol-1-yl)-3'-deoxythymidine...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314844(3'-Deoxy-3'-(4-phenyl-1,2,3-triazol-1-yl)-beta-(E)...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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