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Found 111 with Last Name = 'vandenabeele' and Initial = 'p'
TargetAurora kinase A(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant AurKA after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)
Affinity DataIC50:  68nMAssay Description:Inhibition of human recombinant AurKB after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263058(CHEMBL4090723)
Affinity DataIC50:  167nMAssay Description:Inhibition of human recombinant RIPK1 after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263059(CHEMBL4105556)
Affinity DataIC50:  178nMAssay Description:Inhibition of human recombinant RIPK1 after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)
Affinity DataIC50:  208nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263056(CHEMBL4064515)
Affinity DataIC50:  210nMAssay Description:Inhibition of human recombinant AurKA after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263056(CHEMBL4064515)
Affinity DataIC50:  229nMAssay Description:Inhibition of human recombinant AurKB after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263059(CHEMBL4105556)
Affinity DataIC50:  293nMAssay Description:Inhibition of human recombinant AurKA after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263046(CHEMBL4069729)
Affinity DataIC50:  295nMAssay Description:Inhibition of human recombinant RIPK1 after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263046(CHEMBL4069729)
Affinity DataIC50:  310nMAssay Description:Inhibition of human recombinant AurKA after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263072(CHEMBL4080426)
Affinity DataIC50:  360nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263072(CHEMBL4080426)
Affinity DataIC50:  380nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263078(CHEMBL4069988)
Affinity DataIC50:  390nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263058(CHEMBL4090723)
Affinity DataIC50:  430nMAssay Description:Inhibition of human recombinant AurKA after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263058(CHEMBL4090723)
Affinity DataIC50:  430nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263058(CHEMBL4090723)
Affinity DataIC50:  430nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263046(CHEMBL4069729)
Affinity DataIC50:  530nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263163(CHEMBL4099814)
Affinity DataIC50:  640nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263059(CHEMBL4105556)
Affinity DataIC50:  640nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263046(CHEMBL4069729)
Affinity DataIC50:  680nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263089(CHEMBL4077434)
Affinity DataIC50:  700nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263057(CHEMBL381230)
Affinity DataIC50:  754nMAssay Description:Inhibition of human recombinant RIPK1 after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263078(CHEMBL4069988)
Affinity DataIC50:  810nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263058(CHEMBL4090723)
Affinity DataIC50:  853nMAssay Description:Inhibition of human recombinant AurKB after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263085(CHEMBL4102307)
Affinity DataIC50:  910nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263046(CHEMBL4069729)
Affinity DataIC50:  959nMAssay Description:Inhibition of human recombinant AurKB after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)
Affinity DataIC50:  980nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263059(CHEMBL4105556)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263159(CHEMBL4065014)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263164(CHEMBL4086975)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263059(CHEMBL4105556)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of human recombinant AurKB after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263089(CHEMBL4077434)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263163(CHEMBL4099814)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263099(CHEMBL4084466)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263079(CHEMBL4089624)
Affinity DataIC50:  1.74E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263079(CHEMBL4089624)
Affinity DataIC50:  1.74E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263085(CHEMBL4102307)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263161(CHEMBL4064167)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263084(CHEMBL4081804)
Affinity DataIC50:  1.94E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263056(CHEMBL4064515)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibition of human recombinant RIPK1 after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263159(CHEMBL4065014)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263057(CHEMBL381230)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human recombinant AurKA after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263057(CHEMBL381230)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human recombinant AurKB after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263080(CHEMBL4075303)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263084(CHEMBL4081804)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263086(CHEMBL4083590)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263087(CHEMBL4070219)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263097(CHEMBL4094672)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263098(CHEMBL4074165)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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