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Found 94 with Last Name = 'vekemans' and Initial = 'ja'
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50125935((R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic ac...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50125935((R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic ac...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307231(1-(4-Cyanobenzyl)-5-phenyl-1H-imidazole | CHEMBL59...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307242(1-(4-Cyanobenzyl)-5-(2-fluorophenyl)-1H-imidazole ...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307220(CHEMBL591229 | Methyl 3-[1-(4-Cyanobenzyl)-1H-imid...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307243(1-(4-Cyanobenzyl)-5-(2-methylphenyl)-1H-imidazole ...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307223(CHEMBL592614 | Methyl 3-[1-(4-Bromobenzyl)-1H-imid...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM24655(1-benzyl-5-phenyl-1H-imidazole | 4-phenylimidazole...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307234(1-(4-Bromobenzyl)-5-phenyl-1H-imidazole | CHEMBL59...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307245(1-(4-Cyanobenzyl)-5-(3-methylphenyl)-1H-imidazole ...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307244(1-(4-Cyanobenzyl)-5-(3-fluorophenyl)-1H-imidazole ...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307243(1-(4-Cyanobenzyl)-5-(2-methylphenyl)-1H-imidazole ...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307233(1-(4-Chlorobenzyl)-5-phenyl-1H-imidazole | CHEMBL5...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307229(3-[1-(4-Bromobenzyl)-1H-imidazol-5-yl]-1-propanol ...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307245(1-(4-Cyanobenzyl)-5-(3-methylphenyl)-1H-imidazole ...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307237(1-(4-Cyanobenzyl)-5-(methyl carboxylate)-1H-imidaz...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307234(1-(4-Bromobenzyl)-5-phenyl-1H-imidazole | CHEMBL59...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307232(1-(4-Fluorobenzyl)-5-phenyl-1H-imidazole | CHEMBL6...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307235(1-(4-Methoxybenzyl)-5-phenyl-1H-imidazole | CHEMBL...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM24655(1-benzyl-5-phenyl-1H-imidazole | 4-phenylimidazole...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307230(3-[1-(4-Methoxybenzyl)-1H-imidazol-5-yl]-1-propano...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50008729(1-(4-Cyanobenzyl)-5-methyl-1H-imidazole | 4-(5-Met...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307226(3-[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]-1-propanol ...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307235(1-(4-Methoxybenzyl)-5-phenyl-1H-imidazole | CHEMBL...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307232(1-(4-Fluorobenzyl)-5-phenyl-1H-imidazole | CHEMBL6...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307227(3-[1-(4-Fluorobenzyl)-1H-imidazol-5-yl]-1-propanol...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307229(3-[1-(4-Bromobenzyl)-1H-imidazol-5-yl]-1-propanol ...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307242(1-(4-Cyanobenzyl)-5-(2-fluorophenyl)-1H-imidazole ...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307238(1-(4-Cyanobenzyl)-5-bromo-1H-imidazole | CHEMBL599...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307246(1-(4-Cyanobenzyl)-5-(4-fluorophenyl)-1H-imidazole ...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307233(1-(4-Chlorobenzyl)-5-phenyl-1H-imidazole | CHEMBL5...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307246(1-(4-Cyanobenzyl)-5-(4-fluorophenyl)-1H-imidazole ...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307231(1-(4-Cyanobenzyl)-5-phenyl-1H-imidazole | CHEMBL59...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307240(1-(4-Cyanobenzyl)-5-hydroxymethyl-1H-imidazole | C...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307220(CHEMBL591229 | Methyl 3-[1-(4-Cyanobenzyl)-1H-imid...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307244(1-(4-Cyanobenzyl)-5-(3-fluorophenyl)-1H-imidazole ...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM9920((S)Fadrozole | 4-[(5S)-5,6,7,8-tetrahydroimidazo[1...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307236(1-(4-Cyanobenzyl)-5-(methylene-acetate)-1H-imidazo...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307228(3-[1-(4-Chlorobenzyl)-1H-imidazol-5-yl]-1-propanol...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307237(1-(4-Cyanobenzyl)-5-(methyl carboxylate)-1H-imidaz...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307226(3-[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]-1-propanol ...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307221(CHEMBL599622 | Methyl 3-[1-(4-Fluorobenzyl)-1H-imi...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307228(3-[1-(4-Chlorobenzyl)-1H-imidazol-5-yl]-1-propanol...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307223(CHEMBL592614 | Methyl 3-[1-(4-Bromobenzyl)-1H-imid...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307230(3-[1-(4-Methoxybenzyl)-1H-imidazol-5-yl]-1-propano...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307239(1-(4-Cyanobenzyl)-5-formyl-1H-imidazole | CHEMBL61...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307238(1-(4-Cyanobenzyl)-5-bromo-1H-imidazole | CHEMBL599...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307221(CHEMBL599622 | Methyl 3-[1-(4-Fluorobenzyl)-1H-imi...)
Affinity DataIC50:  104nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Eindhoven University Of Technology

Curated by ChEMBL
LigandPNGBDBM50307224(CHEMBL599624 | Methyl 3-[1-(4-Methoxybenzyl)-1H-im...)
Affinity DataIC50:  111nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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