Affinity DataKi: 0.680nMAssay Description:Mixed-type inhibition of recombinant human AChE assessed as inhibition constant using acetylthiocholine iodide as substrate by Cornish-Bowden plot an...More data for this Ligand-Target Pair
Affinity DataKi: 0.940nMAssay Description:Mixed-type inhibition of recombinant human AChE assessed as dissociation constant for protein-substrate-compound complex using acetylthiocholine iodi...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Competitive inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate assessed as dissociation constant for enzyme-inhibitor complex by Li...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate assessed as dissociation constant for enzyme-substrate-inhibitor com...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and
(+)-(Ib) was evaluated spectrophotometrically at 25° C. by the
method of Ellma...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and
(+)-(Ib) was evaluated spectrophotometrically at 25° C. by the
method of Ellma...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and
(+)-(Ib) was evaluated spectrophotometrically at 25° C. by the
method of Ellma...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Affinity DataIC50: 0.570nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:Inhibition of recombinant Anopheles gambiae wild type AChE after 60 mins by Ellman assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and
(+)-(Ib) was evaluated spectrophotometrically at 25° C. by the
method of Ellma...More data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.740nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.740nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.770nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Affinity DataIC50: 0.820nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Affinity DataIC50: 0.820nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant Anopheles gambiae wild type AChE after 10 mins by Ellman assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant Anopheles gambiae wild type AChE after 60 mins by Ellman assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant Anopheles gambiae wild type AChE after 60 mins by Ellman assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Affinity DataIC50: 1.74nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Affinity DataIC50: 1.86nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior substrate addition measured after 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant Anopheles gambiae wild type AChE after 60 mins by Ellman assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.16nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)
Curated by ChEMBL
Affinity DataIC50: 2.28nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant human AChE after 60 mins by Ellman assayMore data for this Ligand-Target Pair