Affinity DataIC50: 3.5nMAssay Description:Compound was tested for in vitro for AII receptor antagonistic activity in bovine adrenal cortex.More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 3.98nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In vitro Angiotensin II receptor antagonist activity in rat adrenal cortex tissue.More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 5.01nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:In vitro Angiotensin II receptor antagonist activity in rat adrenal cortex tissue.More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 6.31nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 6.31nMAssay Description:Inhibition of IKK1 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 6.31nMAssay Description:Inhibition of IKK1 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 6.31nMAssay Description:Inhibition of IKK1 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 6.31nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 7.94nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 7.94nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 7.94nMAssay Description:Inhibition of IKK1 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 7.94nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 7.94nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:In vitro Angiotensin II receptor antagonist activity in rat adrenal cortex tissue.More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 12.6nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 12.6nMAssay Description:Inhibition of IKK1 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 15.8nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 15.8nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 15.8nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:In vitro binding affinity to angiotensin II receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Binding affinity expressed as inhibitory concentration against angiotensin II receptor of rat adrenal cortexMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Binding affinity of the compound expressed as inhibitory concentration towards bovine adrenal cortex angiotensin II receptor was measuredMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 19.9nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 19.9nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 19.9nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 19.9nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 19.9nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:In vitro Angiotensin II receptor antagonism in bovine adrenal cortex tissue.More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 25.1nMAssay Description:Inhibition of IKK1 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Binding affinity expressed as inhibitory concentration against angiotensin II receptor of rat adrenal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:In vitro binding affinity to angiotensin II receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:In vitro Angiotensin II receptor antagonism in bovine adrenal cortex tissue.More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Compound was tested for in vitro for AII receptor antagonistic activity in bovine adrenal cortex.More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:In vitro Angiotensin II receptor antagonism in bovine adrenal cortex tissue.More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:In vitro binding affinity to angiotensin II receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:In vitro Angiotensin II receptor antagonism in bovine adrenal cortex tissue.More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 31.6nMAssay Description:Inhibition of IKK1 in presence of 1 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:In vitro binding affinity to angiotensin II receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:In vitro Angiotensin II receptor antagonism in bovine adrenal cortex tissue.More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:In vitro Angiotensin II receptor antagonism in bovine adrenal cortex tissue.More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Binding affinity of the compound expressed as inhibitory concentration towards bovine adrenal cortex angiotensin II receptor was measuredMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Binding affinity of the compound expressed as inhibitory concentration towards bovine adrenal cortex angiotensin II receptor was measuredMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:In vitro Angiotensin II receptor antagonism in bovine adrenal cortex tissue.More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:In vitro binding affinity to angiotensin II receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:In vitro Angiotensin II receptor antagonism in bovine adrenal cortex tissue.More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 39.8nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:In vitro binding affinity to angiotensin II receptor in bovine adrenal cortexMore data for this Ligand-Target Pair