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Found 441 with Last Name = 'vischer' and Initial = 'hf'
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM112780(US8629135, SW-07)
Affinity DataKi:  0.178nMAssay Description:Displacement of [3H]mepyramine from human H1R expressed in HEK293T cell homogenates incubated for 1 hr by radioligand binding assay based liquid scin...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50079527((3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimet...)
Affinity DataKi:  0.178nMAssay Description:Displacement of [3H]mepyramine from human histamine H1 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50079527((3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimet...)
Affinity DataKi:  0.251nMAssay Description:Displacement of [3H]mepyramine from human wild type N-terminal hemagglutinin-tagged histamine H1 receptor expressed in HEK293T cells after 4 hrs by m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50031228(CHEMBL420316)
Affinity DataKi:  0.398nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516710(CHEMBL4469024)
Affinity DataKi:  0.417nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22542(4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...)
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516713(CHEMBL4448535)
Affinity DataKi:  0.631nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22916(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Affinity DataKi:  0.631nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516707(CHEMBL4588983)
Affinity DataKi:  0.794nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516717(CHEMBL4582006)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50514105(CHEMBL4441731)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]NAMH from mouse H3R expressed in HEK293T cells incubated for 2 hrs by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419448(CHEMBL1923026)
Affinity DataKi:  1.02nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419444(CHEMBL43934 | VUF-5228)
Affinity DataKi:  1.05nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419456(CHEMBL1923034)
Affinity DataKi:  1.15nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516716(CHEMBL4474226)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM22567(3H]pyrilamine | CHEMBL511 | Dorantamin | Mepyramin...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]mepyramine from human wild type N-terminal hemagglutinin-tagged histamine H1 receptor expressed in HEK293T cells after 4 hrs by m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22911(2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide |...)
Affinity DataKi:  1.58nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419048(CHEMBL1824048)
Affinity DataKi:  1.58nMAssay Description:Displacement of [3H]granisetron from human 5-HT3AR expressed in HEK293 cells after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50073179(8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-be...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419455(CHEMBL1923033)
Affinity DataKi:  1.62nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516706(CHEMBL4514700)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50202722(CHEMBL3906929)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]mepyramine from human wild type N-terminal hemagglutinin-tagged histamine H1 receptor expressed in HEK293T cells after 4 hrs by m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM22567(3H]pyrilamine | CHEMBL511 | Dorantamin | Mepyramin...)
Affinity DataKi:  2.09nMAssay Description:Displacement of [3H]mepyramine from human histamine H1 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516708(CHEMBL4581343)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516719(CHEMBL4554533)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50202830(CHEMBL3905009)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]mepyramine from human wild type N-terminal hemagglutinin-tagged histamine H1 receptor expressed in HEK293T cells after 4 hrs by m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22541(Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...)
Affinity DataKi:  2.82nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50491206(CHEMBL2375772)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]histamine displacement from human recombinant histamine H4 receptor expressed in SK-NM-C cells after 45 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50342989(CHEMBL1771000 | N4-isobutyl-6-(4-methylpiperazin-1...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]histamine displacement from human recombinant histamine H4 receptor expressed in SK-NM-C cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50491219(CHEMBL493720)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]histamine displacement from human recombinant histamine H4 receptor expressed in SK-NM-C cells after 45 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50202726(CHEMBL3955589)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]mepyramine from human wild type N-terminal hemagglutinin-tagged histamine H1 receptor expressed in HEK293T cells after 4 hrs by m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516704(CHEMBL4442502)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516709(CHEMBL4588726)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50514105(CHEMBL4441731)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]NAMH from human H3R expressed in HEK293T cells incubated for 2 hrs by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516703(CHEMBL4516137)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50036935(8-Chloro-11-[1-(5-methyl-pyridin-3-ylmethyl)-piper...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516705(CHEMBL4454015)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516720(CHEMBL4474559)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50606429(CHEMBL5175488)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]mepyramine from human H1R expressed in HEK293T cells by radioligand competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419454(CHEMBL1923032)
Affinity DataKi:  4.68nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419449(CHEMBL1923027)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516715(CHEMBL4450560)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50516711(CHEMBL90893)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]mepyramine from N-terminal HA-tagged H1R (unknown origin) expressed in HEK293T cells measured after 4 hrs by microbeta scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50202831(CHEMBL3962094)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]mepyramine from human wild type N-terminal hemagglutinin-tagged histamine H1 receptor expressed in HEK293T cells after 4 hrs by m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50202728(CHEMBL3910939)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]mepyramine from human wild type N-terminal hemagglutinin-tagged histamine H1 receptor expressed in HEK293T cells after 4 hrs by m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Nottingham Biodiscovery Institute

Curated by ChEMBL
LigandPNGBDBM50358532(CHEMBL1923521)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]mepyramine from human histamine H1 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50491203(CHEMBL2375757)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]histamine displacement from human histamine H4 receptor expressed in SK-NM-C cells after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM22566(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]histamine displacement from human recombinant histamine H4 receptor expressed in SK-NM-C cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50514097(CHEMBL4466700)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]NAMH from human H3R expressed in HEK293T cells incubated for 2 hrs by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM26390(4-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-2-ami...)
Affinity DataKi:  6.31nMAssay Description:Displacement of [3H]histamine from human H4R receptor expressed in HEK293 cells at 10 uM after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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