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Found 223 with Last Name = 'vitte' and Initial = 'pa'
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189760(5-[5-(2,4-dihydroxyphenyl)furan-2-ylmethylene]thia...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189741(5-[5-(2,5-dihydroxyphenyl)furan-2-ylmethylene]thia...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189752(5-[5-(3,5-difluoro-2-hydroxyphenyl)furan-2-ylmethy...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189748(4-[5-(2,4-dioxothiazolidin-5-ylidenemethyl)furan-2...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189750(5-[5-(2-hydroxyphenyl)furan-2-ylmethylene]thiazoli...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189744((Z)-5-((5-(4-fluoro-2-hydroxyphenyl)furan-2-yl)met...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189743(5-[5-(5-fluoro-2-hydroxyphenyl)furan-2-ylmethylene...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189745(5-[5-(2-hydroxy-5-methylphenyl)furan-2-ylmethylene...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189751(3-[5-(2,4-dioxothiazolidin-5-ylidenemethyl)furan-2...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169985(4-(2-(4-(benzo[d]thiazol-2(3H)-ylidene(cyano)methy...)
Affinity DataIC50:  41nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189753(5-[5-(2-hydroxy-5-chlorophenyl)furan-2-ylmethylene...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189742(5-[5-(2-hydroxy-5-trifluoromethoxyphenyl)furan-2-y...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169980(CHEMBL363254 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  65nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  70nMAssay Description:Inhibition of c-Jun N-Terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169998(CHEMBL191581 | CHEMBL254651 | [3H-Benzothiazol-(2Z...)
Affinity DataIC50:  80nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170008(CHEMBL372708 | {2-[2-(4-Amino-phenyl)-ethylamino]-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189764(5-[5-(2-hydroxy-3-nitrophenyl)furan-2-ylmethylene]...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189741(5-[5-(2,5-dihydroxyphenyl)furan-2-ylmethylene]thia...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189746(5-(5-pyridin-2-ylfuran-2-ylmethylene)thiazolidine-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169999(CHEMBL371113 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  143nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170017(CHEMBL189841 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  147nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  150nMAssay Description:Inhibition of c-Jun N-Terminal kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189746(5-(5-pyridin-2-ylfuran-2-ylmethylene)thiazolidine-...)
Affinity DataIC50:  185nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189760(5-[5-(2,4-dihydroxyphenyl)furan-2-ylmethylene]thia...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189766(5-((5-(2-hydroxy-5-nitrophenyl)furan-2-yl)methylen...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189748(4-[5-(2,4-dioxothiazolidin-5-ylidenemethyl)furan-2...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189751(3-[5-(2,4-dioxothiazolidin-5-ylidenemethyl)furan-2...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against c-Jun N-Terminal kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169966((2Z)-1,3-benzothiazol-2(3H)-ylidene(2-chloropyrimi...)
Affinity DataIC50:  250nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170001(CHEMBL364637 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  250nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189756(5-[5-(2-fluoro-4-hydroxyphenyl)furan-2-ylmethylene...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169965(CHEMBL363253 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  273nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189755(5-[5-(3-hydroxyphenyl)furan-2-ylmethylene]thiazoli...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  306nMAssay Description:Inhibition of human PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189750(5-[5-(2-hydroxyphenyl)furan-2-ylmethylene]thiazoli...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169977(CHEMBL190742 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  337nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169994(CHEMBL189852 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  340nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189752(5-[5-(3,5-difluoro-2-hydroxyphenyl)furan-2-ylmethy...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170014((2Z)-1,3-benzothiazol-2(3H)-ylidene(6-bromo-2-chlo...)
Affinity DataIC50:  350nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189747(5-[5-(4-hydroxyphenyl)furan-2-ylmethylene]thiazoli...)
Affinity DataIC50:  380nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169967(CHEMBL189223 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  397nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169976(CHEMBL191376 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  407nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189743(5-[5-(5-fluoro-2-hydroxyphenyl)furan-2-ylmethylene...)
Affinity DataIC50:  455nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169978(CHEMBL365963 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  458nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169983(CHEMBL424815 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  473nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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