Found 83 with Last Name = 'voleti' and Initial = 's' TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
3D Structure (crystal)TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human plasma ACEMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Inhibition of Wistar rat plasma ACEMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of ob/ob mouse plasma ACEMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of ob/ob mouse plasma ACEMore data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 155nMAssay Description:Inhibition of Wistar rat plasma DPP4More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 157nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibition of human plasma ACEMore data for this Ligand-Target Pair
Affinity DataIC50: 217nMAssay Description:Inhibition of ob/ob mouse plasma DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 255nMAssay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
Affinity DataIC50: 279nMAssay Description:Inhibition of human plasma ACEMore data for this Ligand-Target Pair
Affinity DataIC50: 319nMAssay Description:Inhibition of Wistar rat plasma DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 334nMAssay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 351nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 488nMAssay Description:Inhibition of ob/ob mouse plasma DPP4More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant PDE4B1 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Inhibition of recombinant PDE4D2 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Pharmaceuticals
Curated by ChEMBL
Glenmark Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 666nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 893nMAssay Description:Inhibition of Wistar rat plasma ACEMore data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of Wistar rat plasma DPP4More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of recombinant PDE4B1 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of ob/ob mouse plasma ACEMore data for this Ligand-Target Pair
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of ob/ob mouse plasma ACEMore data for this Ligand-Target Pair
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of ob/ob mouse plasma DPP4More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of recombinant PDE4D2 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Wistar rat plasma ACEMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 2.89E+3nMAssay Description:Inhibition of recombinant PDE4D2 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 3.33E+3nMAssay Description:Inhibition of recombinant PDE4D2 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of recombinant PDE4B1 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of Wistar rat plasma DPP4More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 4.22E+3nMAssay Description:Inhibition of recombinant PDE4B1 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
