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Found 15 with Last Name = 'vorobiov' and Initial = 'aa'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314762(5-methyl-2-(methylthio)-3-(phenylsulfonyl)-6,7,8,9...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor in humanHeLa cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314759(2-(methylthio)-3-(phenylsulfonyl)-7,8-dihydro-6H-c...)
Affinity DataKi:  0.458nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor in humanHeLa cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314760(2-(methylthio)-3-(phenylsulfonyl)-6,7,8,9-tetrahyd...)
Affinity DataKi:  0.549nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor in humanHeLa cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314763(9-methyl-2-(methylthio)-3-(phenylsulfonyl)-5,6,7,8...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor in humanHeLa cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314761(2-Methylsulfanyl-3-phenylsulfonyl-5,6,7,8-tetrahyd...)
Affinity DataKi:  7.97nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor in humanHeLa cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314759(2-(methylthio)-3-(phenylsulfonyl)-7,8-dihydro-6H-c...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at human 5HT6 receptor in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation pretreated for 15 mins befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314760(2-(methylthio)-3-(phenylsulfonyl)-6,7,8,9-tetrahyd...)
Affinity DataIC50:  7.5nMAssay Description:Antagonist activity at human 5HT6 receptor in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation pretreated for 15 mins befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314763(9-methyl-2-(methylthio)-3-(phenylsulfonyl)-5,6,7,8...)
Affinity DataIC50:  7.80nMAssay Description:Antagonist activity at human 5HT6 receptor in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation pretreated for 15 mins befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314762(5-methyl-2-(methylthio)-3-(phenylsulfonyl)-6,7,8,9...)
Affinity DataIC50:  16.8nMAssay Description:Antagonist activity at human 5HT6 receptor in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation pretreated for 15 mins befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314761(2-Methylsulfanyl-3-phenylsulfonyl-5,6,7,8-tetrahyd...)
Affinity DataIC50:  98.5nMAssay Description:Antagonist activity at human 5HT6 receptor in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation pretreated for 15 mins befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314759(2-(methylthio)-3-(phenylsulfonyl)-7,8-dihydro-6H-c...)
Affinity DataIC50:  118nMAssay Description:Antagonist activity at human 5HT2B receptor in HEK293 cells assessed as inhibition of alphaME-5-HT-induced cAMP accumulation pretreated for 15 secs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314763(9-methyl-2-(methylthio)-3-(phenylsulfonyl)-5,6,7,8...)
Affinity DataIC50:  127nMAssay Description:Antagonist activity at human 5HT2B receptor in HEK293 cells assessed as inhibition of alphaME-5-HT-induced cAMP accumulation pretreated for 15 secs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314762(5-methyl-2-(methylthio)-3-(phenylsulfonyl)-6,7,8,9...)
Affinity DataIC50:  161nMAssay Description:Antagonist activity at human 5HT2B receptor in HEK293 cells assessed as inhibition of alphaME-5-HT-induced cAMP accumulation pretreated for 15 secs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314760(2-(methylthio)-3-(phenylsulfonyl)-6,7,8,9-tetrahyd...)
Affinity DataIC50:  411nMAssay Description:Antagonist activity at human 5HT2B receptor in HEK293 cells assessed as inhibition of alphaME-5-HT-induced cAMP accumulation pretreated for 15 secs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314762(5-methyl-2-(methylthio)-3-(phenylsulfonyl)-6,7,8,9...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of human recombinant ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed