Affinity DataKi: 0.150nMAssay Description:Affinity to human Bradykinin receptor B2 in CHO cell membranes determined by displacement of [3H]-NPC 17731More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.247nMAssay Description:In vitro inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor by Panlabs assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, binding (Experi...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.515nMAssay Description:Compound was tested in vitro for the inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Affinity to human Bradykinin receptor B2 in CHO cell membranes determined by displacement of [3H]-NPC 17731More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.590nMAssay Description:Compound was tested in vitro for the inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.791nMAssay Description:In vitro inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor (Experiment 2)More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of [3H]ZM-241385 binding to adenosine A2a receptor of rat brain tissueMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of [3H]-ZM-241,385 binidng to rat brain adenosine A2a receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, bindingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]GTP-gamma-S, binding (Experi...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Compound was tested in vitro for the inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor (Expe...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]ABA from human adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of [3H]-ZM-241,385 binidng to rat brain adenosine A2a receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of [3H]ZM-241385 binding to adenosine A2a receptor of rat brain tissueMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, binding (Experi...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]-ZM-241,385 binidng to rat brain adenosine A2a receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]ZM-241385 binding to adenosine A2a receptor of rat brain tissueMore data for this Ligand-Target Pair