Affinity DataKi: 0.120nMAssay Description:Inhibitory activity against human carbonic anhydrase IX expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibitory activity against human carbonic anhydrase IX expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.200nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.200nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.210nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.260nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.300nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of human recombinant CA12 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.300nMAssay Description:Inhibition of carbonic anhydrase-2 (unknown origin) incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.300nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitory constant against catalytic domain of human carbonic anhydrase XIIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.300nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase II by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Ki value against human carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of tumor-associated human carbonic anhydrase 9 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.300nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.300nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.300nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Inhibition of human carbonic anhydrase 12 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Inhibitory activity against human carbonic anhydrase IX expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of human carbonic anhydrase 12 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Inhibition of human carbonic anhydrase 12 by CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.390nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Inhibition of human carbonic anhydrase 12 by CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.440nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Ki value against human carbonic anhydrase VIIMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Inhibition of human carbonic anhydrase 14 by CO2 hydration assayMore data for this Ligand-Target Pair
TargetLD26647p(Drosophila melanogaster)
University of Tampere and Tampere University Hospital
Curated by ChEMBL
University of Tampere and Tampere University Hospital
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of Drosophila melanogaster recombinant carbonic anhydrase-2 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins by CO2 hydra...More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Drosophila melanogaster)
University of Tampere and Tampere University Hospital
Curated by ChEMBL
University of Tampere and Tampere University Hospital
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of Drosophila melanogaster recombinant carbonic anhydrase-1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins by CO2 hydra...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of tumor-associated human carbonic anhydrase 9 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.550nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.560nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.560nM ΔG°: -51.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.570nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 10 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine
University Of Agricultural Sciences And Veterinary Medicine
Affinity DataKi: 0.570nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.590nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IMore data for this Ligand-Target Pair