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Found 2128 with Last Name = 'wada' and Initial = 'h'
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344644(8-(2-(diethylamino)ethoxy)-3-ethoxy-6,6-dimethylbe...)
Affinity DataKi:  170nMAssay Description:Competitive inhibition of ALK phosphorylation by Lineweaver-Burk plot analysisChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178978(US9126931, 277)
Affinity DataIC50:  0.168nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179073(US9126931, 823)
Affinity DataIC50:  0.300nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179072(US9126931, 822)
Affinity DataIC50:  0.300nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179071(US9126931, 796)
Affinity DataIC50:  0.300nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178992(US9126931, 338)
Affinity DataIC50:  0.320nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179026(US9126931, 543)
Affinity DataIC50:  0.320nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179002(US9126931, 403)
Affinity DataIC50:  0.391nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178997(US9126931, 359)
Affinity DataIC50:  0.400nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179069(US9126931, 786)
Affinity DataIC50:  0.400nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179033(US9126931, 601)
Affinity DataIC50:  0.456nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179083(US9126931, 882)
Affinity DataIC50:  0.494nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179000(US9126931, 380)
Affinity DataIC50:  0.530nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178993(US9126931, 340)
Affinity DataIC50:  0.580nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179019(US9126931, 486)
Affinity DataIC50:  0.590nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179076(US9126931, 832)
Affinity DataIC50:  0.600nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179075(US9126931, 829)
Affinity DataIC50:  0.700nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179030(US9126931, 579)
Affinity DataIC50:  0.770nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178985(US9126931, 304)
Affinity DataIC50:  0.810nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179079(US9126931, 849)
Affinity DataIC50:  0.813nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179009(US9126931, 429)
Affinity DataIC50:  0.830nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178963(US9126931, 177)
Affinity DataIC50:  0.840nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179027(US9126931, 546)
Affinity DataIC50:  0.860nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178988(US9126931, 319)
Affinity DataIC50:  0.881nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179028(US9126931, 550)
Affinity DataIC50:  0.900nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178980(US9126931, 286)
Affinity DataIC50:  0.952nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178939(US9126931, 109)
Affinity DataIC50:  0.981nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178970(US9126931, 226)
Affinity DataIC50:  0.991nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178987(US9126931, 314)
Affinity DataIC50:  0.996nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178995(US9126931, 355)
Affinity DataIC50:  1.09nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362778(CHEMBL1940182)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of ALK using Bio-Gastrintide as substrate by TR-FRET assay in presence of 30 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362779(CHEMBL1940181 | US9126931, 346)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of ALK using Bio-Gastrintide as substrate by TR-FRET assay in presence of 30 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178981(US9126931, 290)
Affinity DataIC50:  1.13nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179008(US9126931, 426)
Affinity DataIC50:  1.17nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178974(US9126931, 256)
Affinity DataIC50:  1.34nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178928(US9126931, 73)
Affinity DataIC50:  1.40nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088321(CHEMBL292548 | Dimethyl-(tetrahydro-pyran-4-yl)-{4...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179065(US9126931, 760)
Affinity DataIC50:  1.5nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344664(6,6-dimethyl-8-(1-(oxetan-3-yl)piperidin-4-yl)-11-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344664(6,6-dimethyl-8-(1-(oxetan-3-yl)piperidin-4-yl)-11-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of ALK assessed as biotin-EGPWLEEEEEAYGWMDF peptide phosphorylation by TR-FRET assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088302(CHEMBL56565 | Dimethyl-(tetrahydro-pyran-4-yl)-(4-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344664(6,6-dimethyl-8-(1-(oxetan-3-yl)piperidin-4-yl)-11-...)
Affinity DataIC50:  1.53nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179007(US9126931, 424)
Affinity DataIC50:  1.57nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179020(US9126931, 501)
Affinity DataIC50:  1.60nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178979(US9126931, 283)
Affinity DataIC50:  1.63nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178938(US9126931, 104)
Affinity DataIC50:  1.68nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178998(US9126931, 364)
Affinity DataIC50:  1.77nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178990(US9126931, 331)
Affinity DataIC50:  1.78nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088322((4-{[7-(4-Ethoxy-phenyl)-2,3-dihydro-benzo[b]oxepi...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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