TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.0500nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of thymidin synthaseMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 30nM ΔG°: -42.2kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 55nMAssay Description:Binding affinity to guinea pig kappa opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 55nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 60nM ΔG°: -40.5kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Affinity DataKi: 60nM ΔG°: -40.5kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Affinity DataKi: 80nM ΔG°: -39.8kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 121nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 240nM ΔG°: -37.2kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 255nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Inhibition of human Thymidylate synthase by uncompetitive bindingMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibition of human thymidylate synthase AMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of Escherichia coli thymidylate synthase AMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibition of human thymidylate synthase AMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibition of human thymidylate synthase AMore data for this Ligand-Target Pair
Affinity DataKi: 600nM ΔG°: -34.9kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Inhibition of human thymidylate synthase AMore data for this Ligand-Target Pair
Affinity DataKi: 700nM ΔG°: -34.5kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 708nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Inhibition of human thymidylate synthase AMore data for this Ligand-Target Pair