Affinity DataIC50: 0.340nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.530nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.730nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 0.930nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human FPPS using [14C]-IPP and FPP as substrates after 10 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Dana-Farber Cancer Institute
US Patent
Affinity DataIC50: 5nMAssay Description:In vitro kinase assays were conducted at Invitrogen (Madison, Wis.) using the SelectScreen Kinase Profiling Service.More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair