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Found 39 with Last Name = 'wang' and Initial = 'kk'
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50073850((S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyr...)
Affinity DataKi:  10nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50080206(CHEMBL311735 | [1-((4S,5R)-4-Benzyl-5-hydroxy-oxaz...)
Affinity DataKi:  33nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50080206(CHEMBL311735 | [1-((4S,5R)-4-Benzyl-5-hydroxy-oxaz...)
Affinity DataKi:  120nMAssay Description:Tested for inhibitory activity against bovine cathepsin B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50080209(CHEMBL78324 | {1-[((S)-1-Formyl-2-phenyl-ethyl)-me...)
Affinity DataKi:  400nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50080207(CHEMBL80142 | {1-[((S)-1-Formyl-2-phenyl-ethyl)-hy...)
Affinity DataKi:  400nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50366611(CHEMBL1794816)
Affinity DataKi:  1.50E+3nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50080210(Acetic acid (4S,5S)-4-benzyl-3-(2-benzyloxycarbony...)
Affinity DataKi:  2.00E+3nMAssay Description:Tested for inhibitory activity against calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50366612(CHEMBL1794817)
Affinity DataKi:  3.20E+3nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50080208(CHEMBL73869 | [(R)-1-((2R,3S)-3-Benzyl-2-hydroxy-m...)
Affinity DataKi:  5.60E+4nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  7.5nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124017(CHEMBL168909 | N-(1-Formyl-3-methyl-butyl)-3-methy...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124024(2-(4-Chloro-benzenesulfonylamino)-N-[1-formyl-2-(1...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124012(2-(4-Chloro-benzenesulfonylamino)-N-(1-formyl-2-ph...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124022(CHEMBL169307 | N-(1-Formyl-2-phenyl-ethyl)-3-methy...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124019(CHEMBL169551 | N-(1-Formyl-2-phenyl-ethyl)-3-methy...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124018(2-(4-Fluoro-benzenesulfonylamino)-N-[1-formyl-2-(1...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124023(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-2-ph...)
Affinity DataIC50:  27nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124015(CHEMBL168965 | N-(1-Formyl-3-methyl-butyl)-3-methy...)
Affinity DataIC50:  28nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124014(2-(4-Chloro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  78nMAssay Description:Inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124016(2-(4-Fluoro-benzenesulfonylamino)-4-methyl-pentano...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124021(2-(4-Fluoro-benzenesulfonylamino)-5-methyl-hexanoi...)
Affinity DataIC50:  260nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124025(2-(4-Fluoro-benzenesulfonylamino)-3-methyl-N-(1-me...)
Affinity DataIC50:  630nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124020(CHEMBL169121 | N-(1-Formyl-3-methyl-butyl)-2-metha...)
Affinity DataIC50:  830nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50358145(CHEMBL1923968)
Affinity DataIC50:  1.40E+4nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50124013(2-[(4-Fluoro-benzenesulfonyl)-methyl-amino]-N-(1-f...)
Affinity DataIC50:  2.10E+4nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  8.10E+4nMAssay Description:Inhibition of Cytochrome P450 3A4 as BFC substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against coagulation factor VIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against interleukin 1beta converting enzyme (IL-1 beta converting enzyme)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  1.77E+5nMAssay Description:Inhibition of Cytochrome P450 2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory activity against ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  2.91E+5nMAssay Description:Inhibition of Cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  4.92E+5nMAssay Description:Inhibition of Cytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  5.31E+5nMAssay Description:Inhibition of Cytochrome P450 3A4 as BQ substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50358146(CHEMBL1923969)
Affinity DataIC50:  1.00E+6nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of Cytochrome P450 1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed