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Found 18 with Last Name = 'wang' and Initial = 'xk'
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50581481(CHEMBL5089855)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of P-glycoprotein in human LCC6MDR cells assessed as reversal fold by measuring reduction in paclitaxel by measuring paclitaxel IC50 at 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50581480(CHEMBL5088809)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of P-glycoprotein in human LCC6MDR cells assessed as reversal fold by measuring reduction in paclitaxel by measuring paclitaxel IC50 at 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM50055889(CHEMBL3317913)
Affinity DataIC50:  11nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM81939(CAS_52-53-9 | NSC_62969 | VERAPAMIL)
Affinity DataIC50:  38nMAssay Description:Inhibition of P-glycoprotein in human LCC6MDR cells assessed as reversal fold by measuring reduction in paclitaxel by measuring paclitaxel IC50 at 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM50055890(CHEMBL3317912)
Affinity DataIC50:  40nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50581481(CHEMBL5089855)
Affinity DataIC50:  46nMAssay Description:Inhibition of BCRP in HEK293/R2 cells assessed as reversal of topotecan resistance by measuring topotecan IC50 at 1 uM after 5 days by Cell Titer-Glo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM50055887(CHEMBL3317917)
Affinity DataIC50:  46nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM50055891(CHEMBL3317909)
Affinity DataIC50:  72nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM50055884(CHEMBL3317900)
Affinity DataIC50:  79nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50:  85nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM50055886(CHEMBL3317906)
Affinity DataIC50:  86nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM50055885(CHEMBL3317902)
Affinity DataIC50:  95nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50581480(CHEMBL5088809)
Affinity DataIC50:  101nMAssay Description:Inhibition of BCRP in HEK293/R2 cells assessed as reversal of topotecan resistance by measuring topotecan IC50 at 1 uM after 5 days by Cell Titer-Glo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM50055865(CHEMBL3317897)
Affinity DataIC50:  105nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM50055888(CHEMBL3317916)
Affinity DataIC50:  108nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM50055883(CHEMBL3317899)
Affinity DataIC50:  124nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50581480(CHEMBL5088809)
Affinity DataIC50:  341nMAssay Description:Inhibition of MRP1 in human 2008/MRP1 cells assessed as reversal of doxorubicin resistance by measuring doxorubicin IC50 at 1 uM after 5 days by Cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50581481(CHEMBL5089855)
Affinity DataIC50:  354nMAssay Description:Inhibition of MRP1 in human 2008/MRP1 cells assessed as reversal of doxorubicin resistance by measuring doxorubicin IC50 at 1 uM after 5 days by Cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed