TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 970nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of [3H]-9-cis-RA from human GST-tagged N-terminal truncated RXRalpha after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Displacement of [3H]-9-cis-RA from RXRalpha (unknown origin) by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
Affinity DataIC50: 3.08E+3nMAssay Description:Displacement of [3H]-9-cis-RA from human GST-tagged N-terminal truncated RXRalpha after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.15E+3nMAssay Description:Displacement of [3H]-9-cis-RA from human GST-tagged N-terminal truncated RXRalpha after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.73E+3nMAssay Description:Displacement of [3H]-9-cis-RA from human GST-tagged N-terminal truncated RXRalpha after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.71E+3nMAssay Description:Displacement of [3H]-9-cis-RA from human GST-tagged N-terminal truncated RXRalpha after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.29E+3nMAssay Description:Displacement of [3H]-9-cis-RA from human GST-tagged N-terminal truncated RXRalpha after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
Affinity DataIC50: 8.27E+3nMAssay Description:Displacement of [3H]-9-cis-RA from human GST-tagged N-terminal truncated RXRalpha after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.07E+4nMAssay Description:Displacement of [3H]-9-cis-RA from human GST-tagged N-terminal truncated RXRalpha after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair