TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 0.560nMAssay Description:Affinity for Tumor necrosis factor alpha converting enzyme (TACE)More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity was evaluated against matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.840nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Binding affinity for human gelatinase A (MMP-2)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity was evaluated against matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity was evaluated against matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Binding affinity was evaluated against matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Binding affinity was evaluated against matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Binding affinity was evaluated against matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Binding affinity was evaluated against matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition of porcine TNF-alpha converting enzyme(pTACE).More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.61nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of porcine TNF-alpha converting enzyme(pTACE).More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity was evaluated against matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity was evaluated against matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of Matrix metalloproteinase-9(MMP-9)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity was evaluated against matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity was evaluated against matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataKi: <2.10nMAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
Affinity DataKi: <2.10nMAssay Description:Binding affinity for human gelatinase B (MMP-9)More data for this Ligand-Target Pair