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Found 2087 with Last Name = 'weaver' and Initial = 'd'
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM29611(2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Sheep)
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM29611(2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataKi:  0.0631nMAssay Description:Effect on pancreatic polypeptide-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM29611(2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo)
Affinity DataKi:  0.0900nMMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM29611(2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo)
Affinity DataKi:  0.170nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM50034110(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)
Affinity DataKi:  0.210nMMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataKi:  0.230nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1B(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM50035179(Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...)
Affinity DataKi:  0.230nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1A(Sheep)
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataKi:  0.240nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Sheep)
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM50043289(CHEMBL34730 | N-[2-(6-Chloro-5-methoxy-1H-indol-3-...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM50034110(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)
Affinity DataKi:  0.260nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(RAT)
Dvanderbilt Program In Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]NMS from rat recombinant muscarinic M4 receptor expressed in CHO cells after 2 hrs by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(RAT)
Dvanderbilt Program In Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]NMS from rat recombinant muscarinic M4 receptor expressed in CHO cells after 2 hrs by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(RAT)
Dvanderbilt Program In Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]NMS from rat muscarinic M4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM50043289(CHEMBL34730 | N-[2-(6-Chloro-5-methoxy-1H-indol-3-...)
Affinity DataKi:  0.660nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM50035179(Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...)
Affinity DataKi:  0.720nMMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(RAT)
Dvanderbilt Program In Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.860nMAssay Description:Displacement of [3H]NMS from rat recombinant muscarinic M5 receptor expressed in CHO cells after 2 hrs by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataKi:  1.11nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataKi:  1.48nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMuscarinic acetylcholine receptor M5(RAT)
Dvanderbilt Program In Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]NMS from rat muscarinic M5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50302304(1,2-dimethyl-N-(5-methyl-4-(morpholinomethyl)pyrid...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM82509(Melatonin,6-Hydroxy | melatonin, 6-Hydroxy)
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM50043289(CHEMBL34730 | N-[2-(6-Chloro-5-methoxy-1H-indol-3-...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50301311((+/-)3,3,3-trifluoro-2-methyl-N-(8-morpholino-5,6,...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50301315(CHEMBL568467 | N-(3,4-dimethyl-5-(morpholinomethyl...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Sheep)
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM82509(Melatonin,6-Hydroxy | melatonin, 6-Hydroxy)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50277153(4-methyl-3-(morpholinosulfonyl)-N-((1S,2R,4R)-1,3,...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]3methoxy-5-(pyridin-2-ylethynyl)pyridine from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50302299(2,2-dimethyl-N-(5-methyl-4-(morpholinomethyl)pyrid...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataKi:  6.30nMAssay Description:Effect on neuropeptide Y-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataKi:  6.30nMAssay Description:Effect on peptide YY-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cell mem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Massachusetts General Hospital

Curated by PDSP Ki Database
LigandPNGBDBM50043289(CHEMBL34730 | N-[2-(6-Chloro-5-methoxy-1H-indol-3-...)
Affinity DataKi:  6.78nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50302303(1-ethyl-N-(5-methyl-4-(morpholinomethyl)pyridin-2-...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50302295(CHEMBL570792 | N-(5-ethyl-4-(morpholinomethyl)pyri...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50301316(CHEMBL568468 | N-(3,4-dimethyl-5-(morpholinomethyl...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50301311((+/-)3,3,3-trifluoro-2-methyl-N-(8-morpholino-5,6,...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50301311((+/-)3,3,3-trifluoro-2-methyl-N-(8-morpholino-5,6,...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Vanderbilt Institute Of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50231845(CHEMBL255523 | N-(3-chloro-4-(4-ethylpiperazin-1-y...)
Affinity DataKi:  12.7nMAssay Description:Displacement of [3H]NMS from rat muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50302302(1-ethyl-N-(5-methyl-4-(morpholinomethyl)pyridin-2-...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50301312(3,3-difluoro-2-methyl-N-(4-methyl-3-(morpholinomet...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50301306(2-methyl-N-(4-methyl-3-(morpholinomethyl)-5-(trifl...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50301317(4-methyl-3-(morpholinomethyl)-N-((1S,4R)-1,3,3-tri...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50302305(2,2-dimethyl-N-(5-methyl-4-(morpholinomethyl)pyrid...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50301307(CHEMBL577487 | N-(2-fluoro-4-methyl-5-(morpholinom...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50302301(1-ethyl-N-(5-methyl-4-(morpholinomethyl)pyridin-2-...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50301318(4-methyl-3-(2-morpholinoethyl)-N-((1S,4R)-1,3,3-tr...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50301319(4-methyl-3-(3-morpholinopropyl)-N-((1S,4R)-1,3,3-t...)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50302300(1-ethyl-N-(5-methyl-4-(morpholinomethyl)pyridin-2-...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50302294(2,2-dimethyl-N-(6-methyl-4-(morpholinomethyl)pyrid...)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50301313(2-methyl-N-(4-methyl-3-(morpholinomethyl)phenyl)cy...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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