Affinity DataKi: 0.390nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.69nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.32nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.09nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.93nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.47nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 9.5nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Agonist activity at 5-HT4R (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 10.7nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 11.2nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 11.3nMAssay Description:Inhibition of binding to human D4 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 14.7nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 16.4nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 17.5nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 20.7nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 22.3nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 33.5nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 33.7nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 40.4nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 47.5nMAssay Description:Inhibition of binding to human D3 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ
Curated by ChEMBL
Normandie Univ
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 52.5nMAssay Description:Inhibition of binding to human D3 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 56.5nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 65.7nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 79.1nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 82.6nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 92nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 112nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 134nMAssay Description:Inhibition of binding to human D4 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 165nMAssay Description:Inhibition of binding to human D4 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 169nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
Affinity DataKi: 198nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair