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Found 94 with Last Name = 'weithmann' and Initial = 'ku'
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077404(CHEMBL300162 | [(R)-2-(4'-Dimethylamino-biphenyl-4...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077433((R)-7-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077422((R)-2-(5-Pyridin-2-yl-thiophen-2-ylmethanesulfonyl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077416((R)-2-(4'-Dimethylamino-biphenyl-4-sulfonyl)-1,2,3...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077411((R)-2-[4-(4-Dimethylamino-phenoxy)-benzenesulfonyl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077387((R)-2-(4-Butoxy-benzenesulfonyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077440(CHEMBL56137 | {(S)-1-[(S)-3-Hydroxycarbamoyl-2-(4-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077390((R)-2-(4-Phenoxy-benzenesulfonyl)-1,2,3,4-tetrahyd...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077438((R)-2-[4-(4-Fluoro-benzyloxy)-benzenesulfonyl]-1,2...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077370(CHEMBL301675 | Carbonic acid ethyl ester (R)-3-hyd...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077444((R)-7-Amino-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077373((R)-7-Amino-2-(4'-fluoro-biphenyl-4-sulfonyl)-1,2,...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077395((R)-2-(Biphenyl-4-sulfonyl)-1,2,3,4-tetrahydro-iso...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077389((R)-2-(4-Benzoyl-benzenesulfonyl)-1,2,3,4-tetrahyd...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077445(CHEMBL60579 | [(R)-3-Hydroxycarbamoyl-2-(4-methoxy...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077393((R)-5-(4-Methoxy-benzenesulfonyl)-1-methyl-4,5,6,7...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077368((R)-2-(4'-Chloro-biphenyl-4-sulfonyl)-1,2,3,4-tetr...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077450((R)-2-(4-Methoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077443((R)-5-(4-Methoxy-benzenesulfonyl)-4,5,6,7-tetrahyd...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077399((R)-2-(4-Methoxy-benzenesulfonyl)-1,2,3,4-tetrahyd...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077374(CHEMBL294167 | [(R)-2-(4'-Chloro-biphenyl-4-sulfon...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077435((S)-7-((S)-2-Amino-propionylamino)-2-(4-methoxy-be...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077406(CHEMBL57746 | [(R)-7-Amino-2-(4'-chloro-biphenyl-4...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077401((R)-2-(4-Phenoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human neutrophil collagenase, Matrix Metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077410((R)-2-(5-Isoxazol-3-yl-thiophene-2-sulfonyl)-1,2,3...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM16596(4-N,6-N-bis[(4-fluoro-3-methylphenyl)methyl]pyrimi...)
Affinity DataIC50:  8nMpH: 7.5 T: 2°CAssay Description:MMP-13 was assayed its proteolytic activity using a quenched fluorogenic substrate. The substrate hydrolysis was monitored by recording the increase ...More data for this Ligand-Target Pair
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077402(4-Methoxy-benzenesulfonic acid (R)-3-hydroxycarbam...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077403((R)-2-(4-Methoxy-benzenesulfonyl)-7-nitro-1,2,3,4-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077365(CHEMBL417945 | Oxo-[(R)-2-(4-phenoxy-benzenesulfon...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077409(CHEMBL301048 | Oxo-[(R)-2-(4'-trifluoromethyl-biph...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077394(CHEMBL294426 | [(R)-2-(4'-Fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077381((R)-2-(Dibenzofuran-2-sulfonyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077449((S)-3-Benzyloxycarbonylamino-N-[(S)-3-hydroxycarba...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077431(CHEMBL55752 | {(R)-2-[4-(4-Cyano-phenoxy)-benzenes...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077426(CHEMBL57414 | [(R)-2-(Biphenyl-4-sulfonyl)-1,2,3,4...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077447((R)-2-Benzenesulfonyl-1,2,3,4-tetrahydro-isoquinol...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077415(CHEMBL56845 | [(R)-2-(4'-Chloro-biphenyl-4-sulfony...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077377(CHEMBL301900 | [(R)-2-(4'-Chloro-biphenyl-4-sulfon...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077446(CHEMBL55453 | [(R)-2-(2-Biphenyl-4-yl-ethanesulfon...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077385(CHEMBL301626 | [(R)-2-(4'-Fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077382(CHEMBL291697 | [(R)-2-(4'-Fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077396((R)-2-[5-(2-Methylsulfanyl-pyrimidin-4-yl)-thiophe...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077407((R)-2-(2-Phenyl-ethanesulfonyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077432(CHEMBL294654 | {(R)-2-[4-(4-Chloro-phenoxy)-benzen...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077400(CHEMBL298957 | [4-((R)-3-Hydroxycarbamoyl-3,4-dihy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077364(CHEMBL56158 | [(R)-6-tert-Butoxycarbonylamino-2-(4...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077423(CHEMBL293571 | [(R)-2-(4'-Chloro-biphenyl-4-sulfon...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077379((R)-2-(2-Pyridin-4-yl-ethanesulfonyl)-1,2,3,4-tetr...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077367(CHEMBL55321 | {(R)-2-[4-(4-Fluoro-benzyloxy)-benze...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077448(CHEMBL299720 | {(R)-2-[4-(4-Dimethylamino-phenoxy)...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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