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Found 141 with Last Name = 'weitz-schmidt' and Initial = 'g'
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161080((S)-2-[(S)-3-Isobutyl-2,5-dioxo-4-((E)-3-pyridin-4...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145391((1S,3R,8AS)-8-(2-{(4S,6S)-3-(4-HYDROXY-3-METHOXYBE...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145392((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50:  50nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161067((2R)-2-[3-ISOBUTYL-2,5-DIOXO-4-(QUINOLIN-3-YLMETHY...)
Affinity DataIC50:  69nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123241((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123241((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...)
Affinity DataIC50:  70nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123239((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...)
Affinity DataIC50:  110nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145392((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161072((S)-2-((S)-3-Isobutyl-2,5-dioxo-4-quinolin-6-yl-[1...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145394((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  170nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145391((1S,3R,8AS)-8-(2-{(4S,6S)-3-(4-HYDROXY-3-METHOXYBE...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145395((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50:  270nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161065((S)-2-((R)-3-Isobutyl-2,5-dioxo-4-quinolin-3-ylmet...)
Affinity DataIC50:  510nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145396((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-3,7-di...)
Affinity DataIC50:  620nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145390((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50:  640nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145388((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50:  680nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123244((S)-2-((3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-phenyla...)
Affinity DataIC50:  750nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161071((S)-2-[(S)-4-(4-Dimethylamino-benzyl)-3-isobutyl-2...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145398((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145385(4-((1R,5R)-6-{2-[(1S,2S,6R,8S,8aR)-2,6-Dimethyl-8-...)
Affinity DataIC50:  870nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161076((S)-2-[(S)-3-Isobutyl-4-(3-methyl-quinolin-5-ylmet...)
Affinity DataIC50:  890nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161082((S)-2-[(S)-4-(4-Hydroxy-3-methoxy-benzyl)-3-isobut...)
Affinity DataIC50:  950nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123237((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-pyri...)
Affinity DataIC50:  970nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145397((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145386((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145393((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123242((S)-2-{(3S,5R)-4-[2-(4-Bromo-phenyl)-acetyl]-3-iso...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161078((S)-2-[(S)-4-(3-Hydroxy-benzyl)-3-isobutyl-2,5-dio...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145399((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123240((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-4-(2-naphthalen...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145397((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  2.59E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123245((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161068((S)-2-((S)-4-Benzyl-3-isobutyl-2,5-dioxo-[1,4]diaz...)
Affinity DataIC50:  2.85E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161069((S)-2-[(S)-4-(4-Bromo-benzyl)-3-isobutyl-2,5-dioxo...)
Affinity DataIC50:  2.95E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161075((S)-2-[(S)-4-(4-Bromo-cyclohexa-1,3-dienylmethyl)-...)
Affinity DataIC50:  2.95E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145387((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161073((S)-2-[(S)-3-Isobutyl-2,5-dioxo-4-(pyridin-4-ylcar...)
Affinity DataIC50:  3.70E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50071587(2-[2-(3,4,5-Trihydroxy-6-{3-[4-(4-phenoxy-phenoxy)...)
Affinity DataIC50:  4.00E+3nMAssay Description:Compound was tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay B) in P-selectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161070((R)-2-((R)-3-Isobutyl-2,5-dioxo-4-quinolin-3-ylmet...)
Affinity DataIC50:  4.20E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145388((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50071583(2-{{2-[6-(4-{2-[2-(2-Ethoxy-ethoxy)-ethoxy]-ethoxy...)
Affinity DataIC50:  5.00E+3nMAssay Description:Compound was tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay B) in P-selectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50071583(2-{{2-[6-(4-{2-[2-(2-Ethoxy-ethoxy)-ethoxy]-ethoxy...)
Affinity DataIC50:  5.00E+3nMAssay Description:Compound was tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay B) in P-selectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145386((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50:  5.59E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161074((R)-2-((S)-3-Isobutyl-2,5-dioxo-4-quinolin-3-ylmet...)
Affinity DataIC50:  5.70E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145394((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  6.42E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145395((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of HUT78 cell adhesion to immobilized ICAM-1 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161077((S)-2-[(S)-4-(3-Benzyloxy-benzyl)-3-isobutyl-2,5-d...)
Affinity DataIC50:  6.60E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145387((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50:  7.69E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50145398((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)
Affinity DataIC50:  9.50E+3nMAssay Description:In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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