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Found 263 with Last Name = 'wright' and Initial = 'mb'
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317628(4-{2-(2-Carboxy-ethyl)-3-[6-(3,5-di-pyridin-4-yl-p...)
Affinity DataIC50:  0.0700nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317631(4-{2-(2-Carboxy-ethyl)-3-[6-(3'-fluoro-5-pyridin-4...)
Affinity DataIC50:  0.180nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317632(4-{2-(2-Carboxy-ethyl)-3-[6-(3-pyridin-4-yl-5-thio...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317625(4-{2-(2-Carboxyethyl)-3-[6-([1,1',3,1'']terphenyl-...)
Affinity DataIC50:  0.210nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317633(4-{3-[6-(3-Benzo[1,3]dioxol-5-yl-5-pyridin-4-yl-ph...)
Affinity DataIC50:  0.220nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317634(4-{2-(2-Carboxyethyl)-3-[6-(5-thiophen-3-ylbipheny...)
Affinity DataIC50:  0.360nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317635(4-{3-[6-(3-Benzo[1,3]dioxol-5-yl-5-pyrimidin-5-yl-...)
Affinity DataIC50:  0.380nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317636(4-{2-(2-Carboxy-ethyl)-3-[6-(3-pyrimidin-5-yl-5-th...)
Affinity DataIC50:  0.390nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317626(4-{3-[6-(3-5-Benzo[1,3]dioxolyl-5-thiophen-3-ylphe...)
Affinity DataIC50:  0.440nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)
Affinity DataIC50:  0.480nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317637(4-(2-(2-Carboxy-ethyl)-3-{6-[3-(2-chloro-pyridin-4...)
Affinity DataIC50:  0.570nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317638(4-{2-(2-Carboxy-ethyl)-3-[6-(3,5-di-thiophen-3-yl-...)
Affinity DataIC50:  0.580nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317639(4-[3-[6-(5-Benzo[1,3]dioxol-5-yl-biphenyl-3-yloxy)...)
Affinity DataIC50:  0.580nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317630(4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-2'-fluorobip...)
Affinity DataIC50:  0.610nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192109(2-(4-(benzyl(2,2,2-trifluoroethyl)amino)-3-chlorop...)
Affinity DataIC50:  1nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317623(4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-3'-fluorobip...)
Affinity DataIC50:  1.19nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192148(2-(3-chloro-4-(ethyl(thiazol-4-ylmethyl)amino)phen...)
Affinity DataIC50:  2nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192137(2-(3-chloro-4-(((2-(3-chlorophenyl)-5-methyloxazol...)
Affinity DataIC50:  2nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192134(2-(4-(benzyl(ethyl)amino)-3-chlorophenyl)-1,1,1,3,...)
Affinity DataIC50:  3nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192134(2-(4-(benzyl(ethyl)amino)-3-chlorophenyl)-1,1,1,3,...)
Affinity DataIC50:  3nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192144(2-(3-chloro-4-(ethyl(phenethyl)amino)phenyl)-1,1,1...)
Affinity DataIC50:  3nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192136(2-(4-(ethyl((5-methyl-2-(3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  3nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192109(2-(4-(benzyl(2,2,2-trifluoroethyl)amino)-3-chlorop...)
Affinity DataIC50:  3nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317641(4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-4'-methoxybi...)
Affinity DataIC50:  3.27nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192137(2-(3-chloro-4-(((2-(3-chlorophenyl)-5-methyloxazol...)
Affinity DataIC50:  4nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192117(2-(4-(((2-(3-chlorophenyl)-5-methyloxazol-4-yl)met...)
Affinity DataIC50:  5nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192117(2-(4-(((2-(3-chlorophenyl)-5-methyloxazol-4-yl)met...)
Affinity DataIC50:  5nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317642(4-{2-(2-Carboxyethyl)-3-[6-(3,5-dipyrimidin-5-ylph...)
Affinity DataIC50:  5.35nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317643(4-[3-[6-(3,5-Bis-benzo[1,3]dioxol-5-yl-phenoxy)-he...)
Affinity DataIC50:  5.39nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192113(2-(3-chloro-4-(ethyl((5-methyl-2-(3-(trifluorometh...)
Affinity DataIC50:  6nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192144(2-(3-chloro-4-(ethyl(phenethyl)amino)phenyl)-1,1,1...)
Affinity DataIC50:  6nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192136(2-(4-(ethyl((5-methyl-2-(3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  6nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192113(2-(3-chloro-4-(ethyl((5-methyl-2-(3-(trifluorometh...)
Affinity DataIC50:  7nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192115(3-(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hyd...)
Affinity DataIC50:  7nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192138(CHEMBL215904 | methyl 2-(ethyl(4-(1,1,1,3,3,3-hexa...)
Affinity DataIC50:  8nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317644(4-{2-(2-Carboxy-ethyl)-3-[6-(4,4''-difluoro-[1.1':...)
Affinity DataIC50:  8.5nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192126(1,1,1,3,3,3-hexafluoro-2-(4-(((5-methyl-2-(3-(trif...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317645(4-(2-(2-Carboxy-ethyl)-3-{6-[3'-fluoro-5-(1H-indol...)
Affinity DataIC50:  14.0nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192149(CHEMBL215130 | methyl 4-(2-((2-chloro-4-(1,1,1,3,3...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192126(1,1,1,3,3,3-hexafluoro-2-(4-(((5-methyl-2-(3-(trif...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192150(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydrox...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192152(2-(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hyd...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192148(2-(3-chloro-4-(ethyl(thiazol-4-ylmethyl)amino)phen...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192128(2-(4-(((2-(3-chlorophenyl)-5-methyloxazol-4-yl)met...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192141(CHEMBL384298 | methyl 1-(4-(1,1,1,3,3,3-hexafluoro...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192154(CHEMBL215959 | methyl 2-(4-(2-((2-chloro-4-(1,1,1,...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192118(2-(4-(benzyl(ethyl)amino)phenyl)-1,1,1,3,3,3-hexaf...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192145(CHEMBL383945 | methyl 1-(4-(1,1,1,3,3,3-hexafluoro...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192153(CHEMBL215167 | methyl 2-((2-chloro-4-(1,1,1,3,3,3-...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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