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Found 171 with Last Name = 'xiang' and Initial = 'b'
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50286261((S)-2-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...)
Affinity DataIC50:  0.200nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50286257((2R,3R)-3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl...)
Affinity DataIC50:  0.300nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50286260(4-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...)
Affinity DataIC50:  0.300nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50286253((S)-3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...)
Affinity DataIC50:  0.330nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285678((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50286262(4-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...)
Affinity DataIC50:  0.430nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50009073(4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...)
Affinity DataIC50:  0.440nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranesMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50286255(3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...)
Affinity DataIC50:  0.440nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285677((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185884(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4-p-tol...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50052024(CHEMBL787 | montelukast)
Affinity DataIC50:  0.5nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285683((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50286254(3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...)
Affinity DataIC50:  0.580nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185896(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(4-tr...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50286256((R)-3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...)
Affinity DataIC50:  0.600nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185883(2-(4'-chloro-biphenyl-4-sulfonyl)-4-(1,3-dioxo-1,3...)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285675((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50286259(3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...)
Affinity DataIC50:  0.680nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185871(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(5-fl...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185884(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4-p-tol...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285671(CHEMBL86063 | {1-[(R)-1-{3-[(E)-2-(2,3-Dichloro-th...)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185900(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4'-meth...)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285674((1-{(R)-1-{3-[(E)-2-(2,3-Difluoro-thieno[3,2-b]pyr...)
Affinity DataIC50:  0.760nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50286253((S)-3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...)
Affinity DataIC50:  0.790nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes(different expt)More data for this Ligand-Target Pair
In DepthDetails Article
TargetCollagenase 3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185871(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(5-fl...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185888(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(4-et...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185875(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4'-meth...)
Affinity DataIC50:  0.840nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50374486(CHEMBL408366)
Affinity DataIC50:  0.870nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185900(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4'-meth...)
Affinity DataIC50:  0.960nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185880(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4'-isop...)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50283939((S)-3-{(S)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against binding of [3H]-LTD4 to Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285670((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)
Affinity DataIC50:  1.05nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285672((1-{(R)-1-{3-[2-(2,3-Dichloro-thieno[3,2-b]pyridin...)
Affinity DataIC50:  1.06nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185890(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(4-pr...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285673((1-{(R)-1-{3-[(E)-2-(2-Chloro-thieno[3,2-b]pyridin...)
Affinity DataIC50:  1.16nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185877(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4'-meth...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185899(2-[4-(4-chloro-phenylethynyl)-phenylsulfanyl]-4-(1...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185896(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(4-tr...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185888(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(4-et...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50374494(CHEMBL271736)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185883(2-(4'-chloro-biphenyl-4-sulfonyl)-4-(1,3-dioxo-1,3...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185887(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4-p-tol...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185884(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4-p-tol...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50052019(CHEMBL89768 | L-660771 | MK-571 | Sodium; 3-[{3-[(...)
Affinity DataIC50:  1.5nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185887(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4-p-tol...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185880(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4'-isop...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285676(CHEMBL86302 | [1-((R)-1-{3-[(E)-2-(2,3-Dichloro-th...)
Affinity DataIC50:  1.63nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50374494(CHEMBL271736)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185892(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(4-is...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185871(4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(5-fl...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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