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Found 170 with Last Name = 'xiao' and Initial = 't'
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50102025(4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAP...)
Affinity DataKi:  16nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli ass...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50580856(CHEMBL5074481)
Affinity DataKi:  140nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364455(CHEMBL1950682)
Affinity DataKi:  260nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364455(CHEMBL1950682)
Affinity DataKi:  260nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364457(CHEMBL1950684)
Affinity DataKi:  1.18E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364456(CHEMBL1950683)
Affinity DataKi:  1.63E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364453(CHEMBL1950680)
Affinity DataKi:  2.77E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364453(CHEMBL1950680)
Affinity DataKi:  2.77E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364459(CHEMBL1950686)
Affinity DataKi:  2.87E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364461(CHEMBL1950688)
Affinity DataKi:  2.95E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364460(CHEMBL1950687)
Affinity DataKi:  3.49E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364460(CHEMBL1950687)
Affinity DataKi:  3.49E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364462(CHEMBL1950689)
Affinity DataKi:  3.56E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364463(CHEMBL1950690)
Affinity DataKi:  3.92E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364463(CHEMBL1950690)
Affinity DataKi:  3.92E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364454(CHEMBL1950681)
Affinity DataKi:  3.97E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364458(CHEMBL1950685)
Affinity DataKi:  4.21E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50364458(CHEMBL1950685)
Affinity DataKi:  4.21E+3nMAssay Description:Inhibition of MAO-B in mouse cerebral homogenate using kynuramine as substrate after 30 mins by fluorimetry in the presence of MOA-A inhibitor clorgy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065454(CHEBI:63453 | CHEMBL3348846)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of FGFR1 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50139763(CHEMBL306657 | [(E)-(9S,10S,14S,18S)-18-Carbamoylm...)
Affinity DataIC50:  2nMAssay Description:Inhibition of GST-fused Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065454(CHEBI:63453 | CHEMBL3348846)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of FGFR2 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50580855(CHEMBL1205233)
Affinity DataIC50:  4.30nMAssay Description:Binding affinity to Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065449(CHEMBL3401358)
Affinity DataIC50:  20nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065449(CHEMBL3401358)
Affinity DataIC50:  20nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50102025(4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAP...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065449(CHEMBL3401358)
Affinity DataIC50:  20nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065449(CHEMBL3401358)
Affinity DataIC50:  20nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50085867(2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)...)
Affinity DataIC50:  22nMAssay Description:Binding affinity to Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065454(CHEBI:63453 | CHEMBL3348846)
Affinity DataIC50:  27nMAssay Description:Inhibition of FGFR3 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50072862(CHEMBL117807 | Phosphoric acid mono-[4-((S)-2-acet...)
Affinity DataIC50:  47nMAssay Description:Inhibition of GST-fused human Grb2-SH2 domain expressed in Escherichia coli by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065449(CHEMBL3401358)
Affinity DataIC50:  63nMAssay Description:Inhibition of FGFR2 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065449(CHEMBL3401358)
Affinity DataIC50:  71nMAssay Description:Inhibition of FGFR3 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065449(CHEMBL3401358)
Affinity DataIC50:  82nMAssay Description:Inhibition of FGFR1 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM3428(1-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyri...)
Affinity DataIC50:  110nMAssay Description:Inhibition of FGFR1 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065449(CHEMBL3401358)
Affinity DataIC50:  130nMAssay Description:Inhibition of FGFR4 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM3428(1-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyri...)
Affinity DataIC50:  130nMAssay Description:Inhibition of FGFR2 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM3428(1-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyri...)
Affinity DataIC50:  290nMAssay Description:Inhibition of FGFR3 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50102025(4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAP...)
Affinity DataIC50:  350nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli by ...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM3428(1-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyri...)
Affinity DataIC50:  560nMAssay Description:Inhibition of FGFR4 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50580856(CHEMBL5074481)
Affinity DataIC50:  740nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065437(CHEMBL3401370)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065455(CHEMBL1231606)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065454(CHEBI:63453 | CHEMBL3348846)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of FGFR4 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065438(CHEMBL3401369)
Affinity DataIC50:  3.17E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065443(CHEMBL3401364)
Affinity DataIC50:  4.84E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065444(CHEMBL3401363)
Affinity DataIC50:  5.33E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065437(CHEMBL3401370)
Affinity DataIC50:  6.14E+3nMAssay Description:Inhibition of FGFR2 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065440(CHEMBL3401367)
Affinity DataIC50:  6.28E+3nMAssay Description:Inhibition of FGFR2 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065438(CHEMBL3401369)
Affinity DataIC50:  7.62E+3nMAssay Description:Inhibition of FGFR2 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Health Science Center Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50065446(CHEMBL3401361)
Affinity DataIC50:  8.39E+3nMAssay Description:Inhibition of FGFR2 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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