TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Affinity DataKi: 0.580nMAssay Description:Displacement of (+)-[3H]pentazocine from rat brain sigma1 receptor by competitive binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Affinity DataKi: 0.670nMAssay Description:Binding affinity to human brain sigma1 receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Affinity DataKi: 0.790nMAssay Description:Displacement of (+)-[3H]pentazocine from rat brain sigma1 receptor by competitive binding assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity towards cloned human CRF1 receptor expressed in CHO cells using [125I]-o-CRF as the radioligandMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
TargetEmopamil-binding protein-like(Homo sapiens (Human))
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity to emopamil binding protein (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of (+)-[3H]pentazocine from rat brain sigma1 receptor by competitive binding assayMore data for this Ligand-Target Pair
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Homo sapiens (Human))
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity to EBP (unknown origin)More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]CGS21680 from human cloned adenosine receptor A2A expressed in HEK-293 cell membrane incubated for 60 mins by microbeta counting ...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma1 receptor in rat brain membranesMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]DPCPX from human cloned adenosine receptor A1 expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta counting meth...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligandMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of (+)-[3H]pentazocine from rat brain sigma1 receptor by competitive binding assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligandMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Jiao Tong University
Curated by ChEMBL
Shanghai Jiao Tong University
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of recombinant GST-tagged PTP1B (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrate measured after 2 to 3 min...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]DPCPX from human cloned adenosine receptor A1 expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta counting meth...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligandMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]DPCPX from human cloned adenosine receptor A1 expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta counting meth...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Binding affinity to sigma1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetEmopamil-binding protein-like(Homo sapiens (Human))
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Binding affinity to emopamil binding protein (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Displacement of (+)-[3H]pentazocine from rat brain sigma1 receptor by competitive binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]DPCPX from human cloned adenosine receptor A1 expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta counting meth...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP productionMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligandMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligandMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligandMore data for this Ligand-Target Pair
TargetEmopamil-binding protein-like(Homo sapiens (Human))
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Binding affinity to emopamil binding protein (unknown origin)More data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Displacement of [3H]DPCPX from human cloned adenosine receptor A1 expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta counting meth...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
National Engineering Research Center For The Emergency Drug
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Displacement of [3H]CGS21680 from human cloned adenosine receptor A2A expressed in HEK-293 cell membrane incubated for 60 mins by microbeta counting ...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Key Laboratory Of Radiopharmaceuticals Beijing Normal University
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Binding affinity to human brain sigma1 receptorMore data for this Ligand-Target Pair