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Found 25 with Last Name = 'xue' and Initial = 'st'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016469(CHEMBL514709)
Affinity DataKi:  93nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016480(CHEMBL3265104)
Affinity DataKi:  100nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50229787((4S,5R)-Nutlin-3 | (rac)-(4,5-bis(4-chlorophenyl)-...)
Affinity DataKi:  110nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016470(CHEMBL3265094)
Affinity DataKi:  140nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016478(CHEMBL3265103)
Affinity DataKi:  140nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016476(CHEMBL3265101)
Affinity DataKi:  140nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016475(CHEMBL3265100)
Affinity DataKi:  150nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016477(CHEMBL3265102)
Affinity DataKi:  190nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016474(CHEMBL3265099)
Affinity DataKi:  200nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016468(CHEMBL3265096)
Affinity DataKi:  230nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016468(CHEMBL3265096)
Affinity DataKi:  230nMAssay Description:Binding affinity to MDM2 in human MCF7 cells assessed as inhibition of MDM2-p53 interactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016481(CHEMBL3259872)
Affinity DataKi:  230nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016473(CHEMBL3265098)
Affinity DataKi:  240nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016472(CHEMBL3265097)
Affinity DataKi:  280nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50016471(CHEMBL3265095)
Affinity DataKi:  340nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50014323(2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | 2-Phenyl-benzo...)
Affinity DataIC50:  12nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 5 mins followed by NADPH addition and measured after 20 mi...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataIC50:  22nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 5 mins followed by NADPH addition and measured after 20 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50:  36nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 5 mins followed by NADPH addition and measured after...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50090677(4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfon...)
Affinity DataIC50:  893nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate incubated for 5 mins followed by NADPH addition and measured after 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 2C19(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)
Affinity DataIC50:  2.07E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using omeprazole as substrate incubated for 5 mins followed by NADPH addition and measured after 20 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50564895(CHEMBL4797998)
Affinity DataIC50:  7.84E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 5 mins followed by NADPH addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50564895(CHEMBL4797998)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using omeprazole as substrate incubated for 5 mins followed by NADPH addition and measured after 20 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50564895(CHEMBL4797998)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate incubated for 5 mins followed by NADPH addition and measured after 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50564895(CHEMBL4797998)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 5 mins followed by NADPH addition and measured after 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50564895(CHEMBL4797998)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 5 mins followed by NADPH addition and measured after 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed