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Found 29 with Last Name = 'yagi' and Initial = 'a'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM142001(US8927536, 26)
Affinity DataIC50:  0.300nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50189415(CHEMBL3828637)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-C(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50509567(CHEMBL4455382 | US11213520, Example I-003)
Affinity DataIC50:  1nMAssay Description:Inhibition of CDK8/CyclinC (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM142003(US8927536, 34)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM142008(US8927536, 89)
Affinity DataIC50:  1.30nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM141998(US8927536, 4)
Affinity DataIC50:  1.30nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM142007(US8927536, 88)
Affinity DataIC50:  1.70nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM142000(US8927536, 9)
Affinity DataIC50:  1.80nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM142002(US8927536, 32)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM142006(US8927536, 81)
Affinity DataIC50:  2.20nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM141999(US8927536, 6)
Affinity DataIC50:  2.60nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM141996(US8927536, 2)
Affinity DataIC50:  2.60nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM141995(US8927536, 1)
Affinity DataIC50:  3.30nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM142004(US8927536, 67)
Affinity DataIC50:  5.40nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM141997(US8927536, 3)
Affinity DataIC50:  6.30nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM142005(US8927536, 68)
Affinity DataIC50:  6.70nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50292354(CHEMBL463755 | Isorhamnetin 3,7-disulfate)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50292357(CHEMBL458251 | Tamarixetin 3-glucoside-7-sulfate)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50241354(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(3,4,5-tr...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50292356(CHEMBL457815 | Rhamnazin-3-sulfate)
Affinity DataIC50:  3.01E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  5.01E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50292352(CHEMBL463753 | potassium 2-(3,4-dihydroxyphenyl)-5...)
Affinity DataIC50:  5.09E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50292353(CHEMBL471479 | Percicarin | Persicarin)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50292355(CHEMBL457148 | Rhamnazin)
Affinity DataIC50: >9.10E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM23409(3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-...)
Affinity DataIC50: >9.50E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50509570(CHEMBL4447689)
Affinity DataKd:  600nMAssay Description:Binding affinity to CDK8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50509568(CHEMBL4584784)
Affinity DataKd:  32nMAssay Description:Binding affinity to CDK8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50509567(CHEMBL4455382 | US11213520, Example I-003)
Affinity DataKd:  0.770nMAssay Description:Binding affinity to CDK8 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50509569(CHEMBL4456001)
Affinity DataKd:  30nMAssay Description:Binding affinity to CDK8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed