Affinity DataIC50: 0.120nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity of the compound against Tritiated [3H]- mepyramine binding to histamine H1 receptor in guinea pig cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibitory activity of the compound against Tritiated [3H]- mepyramine binding to Histamine H1 receptor in guinea pig cerebral cortexMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibitory activity of the compound against Tritiated [3H]- mepyramine binding to histamine H1 receptor in guinea pig cerebral cortexMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibitory activity of the compound against Tritiated [3H]- mepyramine binding to histamine H1 receptor in guinea pig cerebral cortexMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 295nMAssay Description:Inhibitory activity of the compound against Tritiated [3H]- mepyramine binding to histamine H1 receptor in guinea pig cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 956nMAssay Description:Inhibitory activity of the compound against Tritiated [3H]- mepyramine binding to histamine H1 receptor in guinea pig cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Tachykinin receptor 1 of rat forebrain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair