TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center
Curated by ChEMBL
Peking University Health Science Center
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of human recombinant N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human JAK2 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as inhibition of acetylcholine hydrolysis after 30 mins by Ellmann's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human gamma secretase assessed as effect on C100Flag substrate cleavageMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center
Curated by ChEMBL
Peking University Health Science Center
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant FAKMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human gamma secretase assessed as effect on C100Flag substrate cleavageMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Shanghai Institute Of Technology
Curated by ChEMBL
Shanghai Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 0.871nMAssay Description:Inhibition of human S6K1 using KKRNRTLTK peptide substrate by radiometric assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Homo sapiens (Human))
Repare Therapeutics
Curated by ChEMBL
Repare Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Homo sapiens (Human))
Repare Therapeutics
Curated by ChEMBL
Repare Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Homo sapiens (Human))
Repare Therapeutics
Curated by ChEMBL
Repare Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human GST-tagged JAK3 using FITC-KGGEEEEYFELVKK as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Translational Research Institute And Department Of Molecular Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair