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Found 153 with Last Name = 'yoneda' and Initial = 'k'
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM179992(US9676720, Example 2)
Affinity DataKi:  0.530nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM179995(US9676720, Example 7)
Affinity DataKi:  0.610nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180045(US9676720, Comparative example 16)
Affinity DataKi:  0.75nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM179994(US9676720, Example 6)
Affinity DataKi:  0.75nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM179998(US9676720, Example 11)
Affinity DataKi:  0.790nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM179996(US9676720, Example 9)
Affinity DataKi:  0.800nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM179993(US9676720, Example 4)
Affinity DataKi:  0.800nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180000(US9676720, Example 14)
Affinity DataKi:  0.900nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM179999(US9676720, Example 12)
Affinity DataKi:  0.940nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180002(US9676720, Example 16)
Affinity DataKi:  0.950nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM179997(US9676720, Example 10)
Affinity DataKi:  0.970nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180003(US9676720, Example 18)
Affinity DataKi:  0.990nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119438(BDBM119693 | US8685986, 12)
Affinity DataKi:  1.10nM ΔG°:  -52.0kJ/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180020(US9676720, Comparative example 8)
Affinity DataKi:  1.10nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180024(US9676720, Comparative example 11)
Affinity DataKi:  1.20nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180019(US9676720, Comparative example 7)
Affinity DataKi:  1.40nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180004(US9676720, Example 19)
Affinity DataKi:  1.40nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180005(US9676720, Comparative example 1)
Affinity DataKi:  1.5nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119442(US8685986, 17)
Affinity DataKi:  1.5nM ΔG°:  -51.2kJ/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180021(US9676720, Comparative example 9)
Affinity DataKi:  1.5nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180022(US9676720, Comparative example 10)
Affinity DataKi:  1.70nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119432(US8685986, 3)
Affinity DataKi:  1.90nM ΔG°:  -50.6kJ/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180025(US9676720, Comparative example 12)
Affinity DataKi:  2nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180018(US9676720, Comparative example 6)
Affinity DataKi:  2.20nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180026(US9676720, Comparative example 13)
Affinity DataKi:  2.60nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119433(US8685986, 4)
Affinity DataKi:  2.80nM ΔG°:  -49.6kJ/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119441(US8685986, 16)
Affinity DataKi:  3.10nM ΔG°:  -49.4kJ/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180038(US9676720, Comparative example 15)
Affinity DataKi:  3.20nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180006(US9676720, Comparative example 2)
Affinity DataKi:  3.80nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119435(US8685986, 6)
Affinity DataKi:  3.80nM ΔG°:  -48.9kJ/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119437(US8685986, 11)
Affinity DataKi:  3.80nM ΔG°:  -48.9kJ/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180007(US9676720, Comparative example 3)
Affinity DataKi:  4.40nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119436(US8685986, 9)
Affinity DataKi:  4.40nM ΔG°:  -48.5kJ/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180046(US9676720, Comparative example 17)
Affinity DataKi:  6.80nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119434(US8685986, 5)
Affinity DataKi:  7nM ΔG°:  -47.3kJ/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119443(US8685986, 18)
Affinity DataKi:  9.20nM ΔG°:  -46.6kJ/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataKi:  9.40nM ΔG°:  -46.6kJ/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180027(US9676720, Comparative example 14)
Affinity DataKi: >10nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180009(US9676720, Comparative example 5)
Affinity DataKi: >10nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM180008(US9676720, Comparative example 4)
Affinity DataKi: >10nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119439(BDBM119694 | US8685986, 13)
Affinity DataKi:  13nM ΔG°:  -45.8kJ/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM50506542(CHEMBL4443289)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]prostaglandin E2 from human EP2 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM50506547(C-533,536-02 | CP-533536-02 | Evatanepag sodium)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]prostaglandin E2 from human EP2 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM50506548(CHEMBL4448995)
Affinity DataKi:  433nMAssay Description:Displacement of [3H]prostaglandin E2 from human EP2 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ube Industries

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataIC50: <3nMAssay Description:Displacement of [3H]prostaglandin E2 from recombinant human full length EP3 receptor expressed in Chem-1 cell membranes after 60 mins by liquid scint...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]prostaglandin E2 from human EP2 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ube Industries

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]prostaglandin E2 from recombinant human full length EP4 receptor expressed in Chem-1 cell membranes after 60 mins by liquid scint...More data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM192306(US9187450, 52)
Affinity DataIC50:  6nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and 5,5'...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM192305(US9187450, 51)
Affinity DataIC50:  6nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and 5,5'...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM192303(US9187450, 49 | US9321747, 2)
Affinity DataIC50:  8nMT: 2°CAssay Description:A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and 5,5'...More data for this Ligand-Target Pair
In DepthDetails US Patent
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