Affinity DataIC50: 1nMAssay Description:Inhibition of Aurora B (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 1 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human Aurora B using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 1 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Hanyang University
Curated by ChEMBL
Hanyang University
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of cRAF1 (unknown origin) at 10 uMMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Hanyang University
Curated by ChEMBL
Hanyang University
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of BRAF V599E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human Aurora B using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Inhibition of P38a/MAPK14 (unknown origin)More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Hanyang University
Curated by ChEMBL
Hanyang University
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Inhibition of cRAF1 (unknown origin) at 10 uMMore data for this Ligand-Target Pair
TargetSalicyl-AMP ligase / salicyl-S-ArCP synthetase(Mycobacterium tuberculosis)
Weill Medical College Of Cornell University
Curated by ChEMBL
Weill Medical College Of Cornell University
Curated by ChEMBL
Affinity DataIC50: 10.7nMAssay Description:Inhibition of adenylation activity of Mycobacterium tuberculosis MbtA after 30 mins by ATP-[32P]pyrophosphate exchange assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Hanyang University
Curated by ChEMBL
Hanyang University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Hanyang University
Curated by ChEMBL
Hanyang University
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of BRAF V599E mutant (unknown origin)More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of GST-tagged human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Hanyang University
Curated by ChEMBL
Hanyang University
Curated by ChEMBL
Affinity DataIC50: 186nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of GST-tagged human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
Affinity DataIC50: 284nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of GST-tagged human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
Affinity DataIC50: 364nMAssay Description:Inhibition of human Aurora B using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of Aurora A (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University
Curated by ChEMBL
Kyung Hee University
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of T type calcium channel Cav3.1 (unknown origin) expressed in HEK293T cells by patch clamp method relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 571nMAssay Description:Inhibition of P38a/MAPK14 (unknown origin)More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of GST-tagged human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
Affinity DataIC50: 607nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 638nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of Aurora A (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Inhibition of Aurora A (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 768nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 801nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University
Curated by ChEMBL
Kyung Hee University
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of T type calcium channel Cav3.1 (unknown origin) expressed in HEK293T cells by patch clamp method relative to controlMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of GST-tagged human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of GST-tagged human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GST-tagged human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of human Aurora B using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University
Curated by ChEMBL
Kyung Hee University
Curated by ChEMBL
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of T type calcium channel Cav3.1 (unknown origin) expressed in HEK293T cells by patch clamp method relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of Aurora A (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Aurora A (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of Aurora A (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of Aurora A (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of Aurora A (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of Aurora A (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of human Aurora B using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of GST-tagged human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa
Curated by ChEMBL
University Of Iowa
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of human Aurora A using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of Aurora B (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.83E+3nMAssay Description:Inhibition of Aurora A (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrsMore data for this Ligand-Target Pair