Found 809 with Last Name = 'yun' and Initial = 'cs' TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.200nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.210nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.240nMAssay Description:Inhibition of crizotinib-resistant ALK G1269A mutant (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescenc...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.240nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.330nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.380nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.400nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.440nMT: 2°CAssay Description:The following experiment was performed in order to measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of ...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.450nMAssay Description:Inhibition of crizotinib-resistant ALK C1156Y mutant (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescenc...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.460nMAssay Description:Inhibition of crizotinib-resistant ALK F1174L mutant (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescenc...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild type ALK (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.5nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.5nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.520nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.523nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.540nMAssay Description:Inhibition of ALK (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescence assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.550nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.600nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.600nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.660nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.670nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.700nMAssay Description:Inhibition of wild type ALK (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.700nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.745nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.780nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.800nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.800nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.840nMT: 2°CAssay Description:The following experiment was performed in order to measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.847nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.850nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.880nMT: 2°CAssay Description:The following experiment was performed in order to measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of ...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
3D Structure (crystal)TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:The following experiment was performed in order to measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of ...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:The following experiment was performed in order to measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of ...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescence assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescence assayMore data for this Ligand-Target Pair
