Affinity DataKi: 150nMAssay Description:HLE-inhibitor (Human Leukocyte Elastase) dissociation constant determined by using Dixon PlotMore data for this Ligand-Target Pair
Affinity DataKi: 430nMAssay Description:Compound was tested for the enzyme inhibitory activity against Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Medichem Research
Curated by ChEMBL
Medichem Research
Curated by ChEMBL
Affinity DataKi: 490nMAssay Description:Inhibitory activity against reverse transcriptase of HIV-1More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:HLE-inhibitor (Human Leukocyte Elastase) dissociation constant determined by using Dixon PlotMore data for this Ligand-Target Pair
Affinity DataKi: 2.80E+3nMAssay Description:HLE-inhibitor (Human Leukocyte Elastase) dissociation constant determined by using Dixon PlotMore data for this Ligand-Target Pair
Affinity DataKi: 7.50E+3nMAssay Description:HLE-inhibitor (Human Leukocyte Elastase) dissociation constant determined by using Dixon PlotMore data for this Ligand-Target Pair
Affinity DataKi: 2.43E+4nMAssay Description:Dissociation constant (KI) of the compound was evaluated as inhibitor of murine liver aromatic L-amino acid decarboxylase (AADC)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 13.8nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 14.2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 14.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 14.6nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair