TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human microsomal CYP1B1-dependent ethoxyresorufin-O-deethylase activity by spectrofluorimetric analysis in presence of NADPH regenerati...More data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10.5nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of human microsomal CYP1B1-dependent ethoxyresorufin-O-deethylase activity by spectrofluorimetric analysis in presence of NADPH regenerati...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Zhengzhou University
Curated by ChEMBL
Zhengzhou University
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Reversible inhibition of wild-type human SHP2 using DiFMUP as substrate and measured by jump dilution assayMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 25.8nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair