Affinity DataKi: 1nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 99nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 142nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 194nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
Affinity DataKi: 261nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 613nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 1.03E+3nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 1.18E+3nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 2.44E+3nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Antagonist activity at rat mGluR1 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of intact cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibitory concentration against adenosine kinase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of intact cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.12nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat mGluR1 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human recombinant TRPV1 expressed in human 1321N1 cells assessed as inhibition of capsaicin-induced calcium influx by FLIPR as...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human recombinant TRPV1 expressed in human 1321N1 cells assessed as inhibition of capsaicin-induced calcium influx by FLIPR as...More data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibitory concentration against adenosine kinase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibitory concentration against adenosine kinase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibitory concentration against adenosine kinase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibitory concentration against adenosine kinase was determinedMore data for this Ligand-Target Pair